# 导管扩张（Duct Dilation）

- 器官 / 系统：阴蒂腺 / 雌性生殖系统（clitoral-gland / reproductive-system-female）
- NTP 数据编号：ntp-0550
- 规范 URL：https://www.labsmart.cn/ntp/clitoral-gland-duct-dilation.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#clitoral-gland-duct-dilation
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/clitoral-gland/Duct-Dilation
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
阴蒂腺导管扩张（Clitoral gland duct dilation）（Figure 1、Figure 2、Figure 3、Figure 4、Figure 5、Figure 6、Figure 7、Figure 8、Figure 9、Figure 10、Figure 11）是老龄啮齿类动物中常见

## 病变描述（中文）
阴蒂腺导管扩张（Clitoral gland duct dilation）（Figure 1、Figure 2、Figure 3、Figure 4、Figure 5、Figure 6、Figure 7、Figure 8、Figure 9、Figure 10、Figure 11）是老龄啮齿类动物中常见的偶然性发现。给予雄激素类固醇也可诱导其发生。阴蒂腺导管扩张常伴有腺组织萎缩。较小导管的上皮衬里可为立方上皮、扁平上皮或角化鳞状上皮。当该病变严重时，扩张的导管可占据阴蒂腺的大部分，扩张导管之间可见腺泡组织残存，且腺体可因导管扩张而明显增大。在小鼠中诊断该病变时须谨慎，因为小鼠通常具有非常 cavernous 的导管而腺组织很少。

## 诊断与分级建议（NTP 共识，中文）
阴蒂腺 - 导管，扩张：当其被视为原发性改变时，应始终予以诊断并给出严重程度分级。由导管扩张引起的阴蒂腺萎缩无需单独诊断，但可在描述中叙述。

## 英文原文 · Comment
Clitoral gland duct dilation ( Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Figure 9 , Figure 10 and Figure 11 ) is a common incidental finding in aging rodents. It has also been induced with administration of androgenic steroids. Dilation of the ducts of the clitoral glands is frequently accompanied by atrophy of the glandular tissue. The epithelial lining of smaller ducts may be cuboidal, flattened, or keratinized squamous epithelium. When this condition is severe, the dilated ducts may occupy the majority of the clitoral gland, with remnants of the acinar tissue evident between the dilated ducts, and the glands may be grossly enlarged due to duct dilation. Care must be taken in diagnosing this lesion in mice because mice typically have very cavernous ducts with little glandular tissue.

## 英文原文 · Recommendation
Clitoral gland - Duct, Dilation should always be diagnosed and given a severity grade when it is considered a primary change. Clitoral gland atrophy caused by duct dilation does not need to be diagnosed separately but can be described in the narrative.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0596.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0595.jpg

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