# 纤维化（Fibrosis）

- 器官 / 系统：阴蒂腺 / 雌性生殖系统（clitoral-gland / reproductive-system-female）
- NTP 数据编号：ntp-0553
- 规范 URL：https://www.labsmart.cn/ntp/clitoral-gland-fibrosis.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#clitoral-gland-fibrosis
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/clitoral-gland/Fibrosis
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
阴蒂腺的间质纤维化（Figure 1）常伴随常见的自发性退行性病变（例如萎缩、导管扩张）。

## 病变描述（中文）
阴蒂腺的间质纤维化（Figure 1）常伴随常见的自发性退行性病变（例如萎缩、导管扩张）。它也可能与慢性或慢性活动性炎症相关。早期纤维化比慢性纤维化的成熟胶原呈现更高的细胞密度外观。

## 诊断与分级建议（NTP 共识，中文）
当阴蒂腺纤维化在其他病变不存在的情况下发生时，应当诊断并赋予严重程度分级。作为炎症病变组成部分存在的纤维化，仅当炎症程度与纤维化程度不相称时（即纤维化比根据炎症严重程度所预期的更为严重）才应诊断。如果纤维化未单独诊断，则应在病理学叙述中予以描述。无论何时诊断纤维化，都应赋予严重程度分级。

## 英文原文 · Comment
Stromal fibrosis of the clitoral gland ( Figure 1 ) often accompanies common spontaneous degenerative lesions (e.g., atrophy, duct dilatation). It may also be associated with chronic or chronic active inflammation. Early fibrosis presents a more densely cellular appearance than the mature collagen of chronic fibrosis.

## 英文原文 · Recommendation
Clitoral gland fibrosis should be diagnosed and assigned a severity grade whenever it occurs in the absence of other lesions. Fibrosis that is present as a component of an inflammatory lesion should be diagnosed only when the degree of inflammation is not commensurate to that of fibrosis (i.e., the fibrosis is more severe than would be expected given the severity of the inflammation). If fibrosis is not diagnosed separately, it should be described in the pathology narrative. Whenever it is diagnosed, fibrosis should be assigned a severity grade.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0598.jpg

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