# 角膜新生血管形成（Cornea Neovascularization）

- 器官 / 系统：眼 / 特殊感觉系统（eye / special-senses-system）
- NTP 数据编号：ntp-0347
- 规范 URL：https://www.labsmart.cn/ntp/eye-cornea-neovascularization.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#eye-cornea-neovascularization
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Cornea-Neovascularization
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
角膜基质（corneal stroma）正常情况下无血管，但各种原因造成的损伤可导致新生血管形成。

## 病变描述（中文）
角膜基质（corneal stroma）正常情况下无血管，但各种原因造成的损伤可导致新生血管形成。角膜新生血管化（corneal neovascularization）（Figure 1、Figure 2）的特征是角膜基质内多支小血管增生。常并发基质炎症和上皮增生。在大多数新生血管化病例中，原发损伤是各种原因引起的炎症。然而，饲喂缺乏某些营养素饲料的实验室啮齿类动物角膜也可发生新生血管化。

## 诊断与分级建议（NTP 共识，中文）
当新生血管化发生而不伴发炎症时，应作出诊断并赋予严重程度分级。当新生血管化被认为是炎症的一个特征时，不应单独诊断，除非严重程度确有必要，但应在病理学叙述中予以描述。

## 英文原文 · Comment
The corneal stroma is normally avascular, but damage from various causes may result in neovascularization. Corneal neovascularization ( Figure 1 and Figure 2 ) is characterized by the proliferation of multiple small blood vessels in the corneal stroma. There is often concurrent stromal inflammation and epithelial hyperplasia. In most cases of neovascularization, the primary insult is inflammation resulting from various causes. However, neovascularization can also develop in the cornea of laboratory rodents fed diets deficient in certain nutrients.

## 英文原文 · Recommendation
When neovascularization occurs without concurrent inflammation, it should be diagnosed and assigned a severity grade. When neovascularization is considered a feature of inflammation, it should not be diagnosed separately, unless warranted by severity, but should be described in the pathology narrative.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0981.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0984.jpg

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