# 眼球萎缩（Phthisis Bulbi）

- 器官 / 系统：眼 / 特殊感觉系统（eye / special-senses-system）
- NTP 数据编号：ntp-0335
- 规范 URL：https://www.labsmart.cn/ntp/eye-phthisis-bulbi.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#eye-phthisis-bulbi
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/PhthisisBulbi
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
眼球痨（phthisis bulbi）（Figure 1、Figure 2、Figure 3、Figure 4）是用于描述“终末期”眼球形态的诊断术语，该形态由多种原因所致的严重损伤引起，例如创伤、炎症、电离辐射或环境光过度暴露，或眶内占位性肿块（如哈德氏腺肿瘤）的物理压迫（Figure 4）。

## 病变描述（中文）
眼球痨（phthisis bulbi）（Figure 1、Figure 2、Figure 3、Figure 4）是用于描述“终末期”眼球形态的诊断术语，该形态由多种原因所致的严重损伤引起，例如创伤、炎症、电离辐射或环境光过度暴露，或眶内占位性肿块（如哈德氏腺肿瘤）的物理压迫（Figure 4）。眼球痨的特征是眼球显著皱缩，伴有眼结构的明显移位和结构紊乱。

## 诊断与分级建议（NTP 共识，中文）
眼球痨应诊断为存在，但不进行严重程度分级。眼部各亚部位的变化不应单独诊断，因为它们已包含在集合性诊断术语“眼球痨”中。如果存在诱发原因（例如异物），应单独诊断，并应在叙述中描述这两种病变之间的关联。

## 英文原文 · Comment
Phthisis bulbi ( Figure 1 , Figure 2 , Figure 3 , and Figure 4 ) is the diagnostic term used for the "end-stage" eye morphology resulting from severe injury from various causes, such as trauma, inflammation, excess exposure to ionizing radiation or ambient light, or physical compression by space-occupying orbital masses, such as neoplasms of the Harderian gland ( Figure 4 ). Phthisis bulbi is characterized by prominent shrinkage of the globe with marked displacement and disorganization of ocular structures.

## 英文原文 · Recommendation
Phthisis bulbi should be diagnosed as present without assignment of a severity grade. Changes in the various ocular subtopographies should not be diagnosed separately as they are included in the collective diagnostic term "phthisis bulbi." If an inciting cause (e.g., a foreign body) is present, it should be diagnosed separately, and the association between the two lesions should be described in the narrative.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0998.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_1001.jpg

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