# 上皮增生（Epithelium Hyperplasia）

- 器官 / 系统：胆囊 / 肝胆系统（gallbladder / hepatobiliary-system）
- NTP 数据编号：ntp-0425
- 规范 URL：https://www.labsmart.cn/ntp/gallbladder-epithelium-hyperplasia.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#gallbladder-epithelium-hyperplasia
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/hepatobiliary-system/gallbladder/Epithelium-Hyperplasia
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
Figure 1、Figure 2 来自一个部分塌陷的正常胆囊。注意肌壁的厚度。

## 病变描述（中文）
Figure 1、Figure 2 来自一个部分塌陷的正常胆囊。注意肌壁的厚度。胆囊增生从乳头状皱襞上的少数细胞到累及大部分黏膜的弥漫性乳头状突起不等（Figure 3、Figure 4，箭头）。衬覆上皮中可能存在玻璃样液滴（hyaline droplets）。

## 诊断与分级建议（NTP 共识，中文）
胆囊黏膜或上皮增生在 NTP 研究中不常见，只要存在就应记录并给出严重程度分级。相关的严重病变，如炎症或玻璃样液滴蓄积，应单独诊断。病理学描述应明确所诊断病例的任何异常特征。

## 英文原文 · Comment
Figure 1 and Figure 2 are from a partially collapsed normal gallbladder. Note the thickness of the muscular wall. Gallbladder hyperplasia varies from a few cells on papillary folds to generalized papillary projections involving most of the mucosa ( Figure 3 and Figure 4 , arrows). Hyaline droplets may be present in the lining epithelium.

## 英文原文 · Recommendation
Mucosal or epithelial hyperplasia of the gallbladder is uncommon in NTP studies and should be recorded whenever present and given a severity grade. Severe associated lesions such as inflammation or hyaline droplet accumulation should be diagnosed separately. The pathology narrative should define any unusual features of the case(s) being diagnosed.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0332.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0337.jpg

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