# 肾小球化生(Glomerulus Metaplasia) - 器官 / 系统:肾脏 / 泌尿系统(kidney / urinary-system) - NTP 数据编号:ntp-0165 - 规范 URL:https://www.labsmart.cn/ntp/kidney-glomerulus-metaplasia.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#kidney-glomerulus-metaplasia - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/kidney/Glomerulus-Metaplasia - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 在小鼠中,Bowman囊的肾小球壁层上皮存在性别二态性。雌性壁层上皮细胞通常呈扁平状(Figure 1),而雄性壁层上皮既可呈立方状也可呈扁平状。 ## 病变描述(中文) 在小鼠中,Bowman囊的肾小球壁层上皮存在性别二态性。雌性壁层上皮细胞通常呈扁平状(Figure 1),而雄性壁层上皮既可呈立方状也可呈扁平状。在由某些雄激素类化合物给药所致的肾小球化生中,雌性壁层上皮变为立方状,或呈雄性样(Figure 2)。 ## 诊断与分级建议(NTP 共识,中文) Bowman囊的肾小球化生应当诊断并给出严重程度分级。相关链接:肾脏 - 肾小管 - 肥大 ## 英文原文 · Comment In the mouse, sexual dimorphism of the glomerular parietal epithelium of Bowman’s capsule exists. The female parietal epithelial cells are typically flattened ( Figure 1 ) and the male parietalepithelium can be both cuboidal and flattened. In glomerular metaplasia, caused by administration of some androgenic compounds, the female parietal epithelium becomes cuboidal, or male-like ( Figure 2 ). ## 英文原文 · Recommendation Glomerular metaplasia of Bowman’s capsule should be diagnosed and given a severity grade. Related Links: Kidney - Renal Tubule - Hypertrophy ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_1071.jpg - https://www.labsmart.cn/ntp-atlas-images/ntp_1078.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn