# 肾小管嗜酸性细胞性增生(Renal Tubule Hyperplasia Oncocytic) - 器官 / 系统:肾脏 / 泌尿系统(kidney / urinary-system) - NTP 数据编号:ntp-0171 - 规范 URL:https://www.labsmart.cn/ntp/kidney-renal-tubule-hyperplasia-oncocytic.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#kidney-renal-tubule-hyperplasia-oncocytic - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/kidney/RenalTubule-HyperplasiaOncocytic - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 嗜酸性细胞增生(oncocytic hyperplasia)的特征是肾小管细胞胞质淡染、呈细颗粒状,细胞核位于中央。 ## 病变描述(中文) 嗜酸性细胞增生(oncocytic hyperplasia)的特征是肾小管细胞胞质淡染、呈细颗粒状,细胞核位于中央。嗜酸性细胞增生在大鼠和小鼠中是一种罕见的病变(Figure 1),据报道起源于集合管。超微结构上,嗜酸性细胞由非典型线粒体构成。嗜酸性细胞增生难以与嗜酸性细胞瘤(oncocytoma)区分,应与其他肾小管增生性病变分别评分。 ## 诊断与分级建议(NTP 共识,中文) 嗜酸性细胞增生应作出诊断并给出严重程度分级。相关链接:肾脏 - 肾小管 - 增生,嗜两性-空泡性;肾脏 - 肾小管 - 非典型肾小管增生 ## 英文原文 · Comment Oncocytic hyperplasia is characterized by tubule cells having lightly staining and finely granular cytoplasm with centralized nuclei. Oncocytic hyperplasia is a rare lesion in the rat and mouse ( Figure 1 ) and reportedly originates in the collecting tubule. Ultrastructurally, oncocytes are composed of atypical mitochondria. Oncocytic hyperplasia is difficult to separate from oncocytoma and should be scored separately from other hyperplastic lesions of the renal tubule. ## 英文原文 · Recommendation Oncocytic hyperplasia should be diagnosed and given a severity grade. Related Links: Kidney - Renal Tubule - Hyperplasia, Amphophilic-Vacuolar Kidney - Renal Tubule - Atypical Tubule Hyperplasia ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_1114.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn