# 黄体囊肿（Corpus Luteum Cyst）

- 器官 / 系统：卵巢 / 雌性生殖系统（ovary / reproductive-system-female）
- NTP 数据编号：ntp-0526
- 规范 URL：https://www.labsmart.cn/ntp/ovary-corpus-luteum-cyst.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#ovary-corpus-luteum-cyst
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/CorpusLuteum-Cyst
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
黄体囊肿（corpora lutea cyst）（Figure 1、Figure 2、Figure 3、Figure 4）比正常黄体大，并可能使卵巢结构变形。

## 病变描述（中文）
黄体囊肿（corpora lutea cyst）（Figure 1、Figure 2、Figure 3、Figure 4）比正常黄体大，并可能使卵巢结构变形。其囊壁完全由数层多边形细胞衬覆，胞质丰富、嗜酸性、呈细空泡状的黄体细胞。囊肿形成于真正的黄体，因此囊腔内无退化卵子的证据。囊性黄体来源于排卵卵泡。若具有功能，这些囊肿可导致持续性、非周期性的孕酮刺激。黄体囊肿必须与未正常填充但随动情周期进展的黄体相鉴别。孕酮受体抑制剂可在大鼠中诱导典型的黄体囊肿。

## 诊断与分级建议（NTP 共识，中文）
卵巢黄体囊肿应予以诊断，但作为背景病变发生的囊肿无需分级。对于黄体囊肿，诊断应包含囊肿类型/部位作为修饰词（即 Ovary, Corpus luteum - Cyst）。若认为囊肿与受试物相关，可对其进行分级以充分表征受试物效应。如适用，诊断中可包含“双侧（bilateral）”和“multiple”术语。

## 英文原文 · Comment
Cysts of the corpora lutea ( Figure 1 , Figure 2 , Figure 3 and Figure 4 are larger than a normal corpus luteum and may distort the ovarian architecture. They are lined completely by several layers of polygonal cells, with abundant eosinophilic, finely vacuolated luteal cells. Cyst formation occurs in a true corpus luteum, so there is no evidence of degenerate ova within the cystic cavity. Cystic corpora lutea are derived from ovulatory follicles. If functional, these cysts may result in prolonged, noncyclic progesterone stimulation. Luteal cysts must be differentiated from corpora lutea that did not fill in normally but that progress through the estrous cycle. Progesterone receptor inhibitors induce typical luteal cysts in rats.

## 英文原文 · Recommendation
Ovarian luteal cysts should be diagnosed, but cysts occurring as background lesions need not be graded. In the case of a luteal cyst, the diagnosis should include the type of cyst/location as a modifier (i.e., Ovary, Corpus luteum - Cyst). If the cysts are thought to be treatment related, they may be graded to fully characterize the treatment effect. If applicable, the terms "bilateral" and "multiple" may be included in the diagnosis.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0616.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0617.jpg

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