# 上皮增生（Epithelium Hyperplasia）

- 器官 / 系统：卵巢 / 雌性生殖系统（ovary / reproductive-system-female）
- NTP 数据编号：ntp-0505
- 规范 URL：https://www.labsmart.cn/ntp/ovary-epithelium-hyperplasia.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#ovary-epithelium-hyperplasia
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/Epithelium-Hyperplasia
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
卵巢表面上皮增生表现为上皮表面的小息肉样突起，以及由胞质嗜碱性（basophilic）的立方上皮细胞索向下生长（Figure 1、Figure 2）。

## 病变描述（中文）
卵巢表面上皮增生表现为上皮表面的小息肉样突起，以及由胞质嗜碱性（basophilic）的立方上皮细胞索向下生长（Figure 1、Figure 2）。上皮细胞增生被认为起源于覆盖卵巢表面的间皮（mesothelium）。过去，这被称为生发上皮（germinal epithelium），但“生发上皮”一词具有误导性，因为覆盖卵巢表面的上皮是腹膜（peritoneum）的延续。上皮细胞增生必须与腺瘤（adenoma）、囊腺瘤（cystadenoma）和肾小管间质肿瘤（tubulostromal neoplasms）相鉴别，也必须与管状（Sertoli细胞样）增生（tubular (Sertoliform) hyperplasia）相鉴别，后者由柱状细胞衬覆的管状结构组成，细胞质边界不清，细胞核位于基底部。

## 诊断与分级建议（NTP 共识，中文）
卵巢，上皮——增生应始终予以诊断并给出严重程度分级。

## 英文原文 · Comment
Proliferation of the epithelium lining the surface of the ovary appears as small polypoid projections from the epithelial surface and as downgrowths of cords of cuboidal epithelium cells with basophilic cytoplasm ( Figure 1 and Figure 2 ). Epithelial cell hyperplasia is thought to be derived from the mesothelium lining the ovarian surface. In the past, this has been referred to as germinal epithelium but the term "germinal epithelium" is misleading, because the epithelium covering the surface of the ovary is a continuation of the peritoneum. Epithelial cell hyperplasia must be distinguished from adenoma, cystadenoma, and tubulostromal neoplasms and from tubular (Sertoliform) hyperplasia, which consists of tubules lined by columnar cells with indistinct cytoplasmic borders and basal nuclei.

## 英文原文 · Recommendation
Ovary, Epithelium - Hyperplasia should always be diagnosed and given a severity grade.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0621.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0620.jpg

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