# 骨性化生（Metaplasia Osseous）

- 器官 / 系统：卵巢 / 雌性生殖系统（ovary / reproductive-system-female）
- NTP 数据编号：ntp-0525
- 规范 URL：https://www.labsmart.cn/ntp/ovary-metaplasia-osseous.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#ovary-metaplasia-osseous
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/MetaplasiaOsseous
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
卵巢骨性化生（osseous metaplasia）（Figure 1、Figure 2）的特征为边界清楚、无包膜的病灶，由骨小梁构成，骨小梁表面衬覆成骨细胞和破骨细胞；

## 病变描述（中文）
卵巢骨性化生（osseous metaplasia）（Figure 1、Figure 2）的特征为边界清楚、无包膜的病灶，由骨小梁构成，骨小梁表面衬覆成骨细胞和破骨细胞；还可见无定形无细胞性嗜碱性物质团块，最可能是钙盐的矿化沉积物，并可见邻近卵巢实质轻度受压。卵巢化生是一种与衰老和卵巢萎缩相关的改变。骨性化生偶有报道，但其机制尚未阐明。

## 诊断与分级建议（NTP 共识，中文）
卵巢——化生，骨性（Metaplasia, Osseous）只要存在即应诊断并分级。

## 英文原文 · Comment
Ovarian osseous metaplasia ( Figure 1 and Figure 2 ) is characterized by a well-circumscribed, unencapsulated focus composed of bony trabeculae lined by osteoblasts and osteoclasts; there may also be clumps of amorphous acellular basophilic material, which are most likely mineralized deposits of calcium salts, and mild compression of adjacent ovarian parenchyma. Ovarian metaplasia is a change associated with aging and ovarian atrophy. Osseous metaplasia has been occasionally reported, but the mechanism has not been elucidated.

## 英文原文 · Recommendation
Ovary - Metaplasia, Osseous should be diagnosed and graded whenever present.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0640.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0642.jpg

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