# 矿物质（Mineral）

- 器官 / 系统：卵巢 / 雌性生殖系统（ovary / reproductive-system-female）
- NTP 数据编号：ntp-0517
- 规范 URL：https://www.labsmart.cn/ntp/ovary-mineral.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#ovary-mineral
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/Mineral
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
卵巢矿化（Figure 1、Figure 2）通常继发于细胞损伤或坏死（即营养不良性矿化）。

## 病变描述（中文）
卵巢矿化（Figure 1、Figure 2）通常继发于细胞损伤或坏死（即营养不良性矿化）。卵巢营养不良性矿化在大鼠和小鼠中已有报道。卵巢矿化可见于黄体，作为正常闭锁过程的一部分；然而，也有报道其与化学物质诱导的卵巢卵泡或黄体闭锁相关。转移性矿化在小鼠和大鼠卵巢中不常见。

## 诊断与分级建议（NTP 共识，中文）
卵巢——当没有坏死或炎症证据时，应对矿物质进行诊断和分级。如果矿化继发于坏死或炎症，且异常严重，若病理学家认为有必要，可将其与坏死或炎症同时诊断。如果矿物质与处理相关，研究病理学家应尝试确定病变的根本原因。如果矿化发生在血栓中，则不应诊断。

## 英文原文 · Comment
Ovarian mineralization ( Figure 1 and Figure 2 ) is usually secondary to cell damage or necrosis (i.e., dystrophic mineralization). Dystrophic mineralization of the ovary has been reported in rats and mice. Ovarian mineralization can be seen in corpora lutea as part of normal atresia; however, it has also been reported in association with chemically induced ovarian follicular or corpora lutea atresia. Metastatic mineralization is uncommon in the ovaries of mice and rats.

## 英文原文 · Recommendation
Ovary - Mineral should be diagnosed and graded when there is no evidence of necrosis or inflammation. If it is secondary to necrosis or inflammation, and is unusually severe, it may be diagnosed concurrently with the necrosis or inflammation if the pathologist feels it is warranted. The study pathologist should attempt to identify the underlying cause of the lesion if mineral is treatment related. Mineralization should not be diagnosed if it occurs in a thrombus.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0645.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0643.jpg

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