# 坏死（Necrosis）

- 器官 / 系统：输卵管 / 雌性生殖系统（oviduct / reproductive-system-female）
- NTP 数据编号：ntp-0546
- 规范 URL：https://www.labsmart.cn/ntp/oviduct-necrosis.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#oviduct-necrosis
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/oviduct/Necrosis
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
输卵管坏死（Oviduct necrosis）在啮齿类动物研究中罕见。它可能是邻近卵巢或子宫相关炎症性改变的结果。

## 病变描述（中文）
输卵管坏死（Oviduct necrosis）在啮齿类动物研究中罕见。它可能是邻近卵巢或子宫相关炎症性改变的结果。输卵管坏死的特征为上皮细胞嗜酸性增强、离散、碎裂和脱落（Figure 1、Figure 2）。细胞核固缩和核碎裂。通常伴有炎症细胞浸润。

## 诊断与分级建议（NTP 共识，中文）
输卵管-坏死（Oviduct - Necrosis）一旦出现即应诊断并分级。继发性病变如炎症或出血，除非严重程度足以需要诊断，否则不应诊断。如果坏死继发于其他病变，如炎症，除非严重程度足以需要诊断，否则不应诊断。

## 英文原文 · Comment
Oviduct necrosis is rarely seen in rodent studies. It may be a result of an associated inflammatory change in the adjacent ovary or uterus. Oviduct necrosis is characterized by hypereosinophilic, dissociated, fragmented, and sloughed epithelial cells ( Figure 1 and Figure 2 ). Nuclei are pyknotic and karyorrhectic. It is usually accompanied by an inflammatory infiltrate.

## 英文原文 · Recommendation
Oviduct - Necrosis should be diagnosed and graded whenever present. Secondary lesions such as inflammation or hemorrhage should not be diagnosed unless warranted by severity. If the necrosis is secondary to another lesion, such as inflammation, it should not be diagnosed unless warranted by severity.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0663.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0660.jpg

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