# 合胞体巨细胞（Syncytial Giant Cell）

- 器官 / 系统：甲状旁腺 / 内分泌系统（parathyroid-gland / endocrine-system）
- NTP 数据编号：ntp-0053
- 规范 URL：https://www.labsmart.cn/ntp/parathyroid-gland-syncytial-giant-cell.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#parathyroid-gland-syncytial-giant-cell
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/parathyroid-gland/SyncytialGiantCell
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
大鼠甲状旁腺中可出现多核合体细胞（multinucleated syncytial cells）。

## 病变描述（中文）
大鼠甲状旁腺中可出现多核合体细胞（multinucleated syncytial cells）。其数量不一，但这些巨细胞可占据腺体达一半。它们由相邻主细胞（chief cells）的胞质融合形成。胞质可呈致密嗜酸性。合体巨细胞被认为不干扰甲状旁腺功能。对于这是否为生前变化尚无共识。一些科学家认为这是死后人为假象。

## 诊断与分级建议（NTP 共识，中文）
推荐对甲状旁腺合体巨细胞形成作出诊断。不需要进行严重程度分级。若两侧甲状旁腺均受累，诊断应限定为双侧性。

## 英文原文 · Comment
Multinucleated syncytial cells occur in the parathyroid of rats. Their number varies, but these giant cells may occupy up to one-half of the gland. They are formed by cytoplasmic fusion of adjacent chief cells. The cytoplasm may be densely eosinophilic. Syncytial giant cells are not believed to interfere with parathyroid function. There is no consensus that this is an antemortem change. Some scientists consider this a postmortem artifact.

## 英文原文 · Recommendation
Diagnosis of syncytial giant cell formation in the parathyroid is recommended. A severity grade is not needed. If both parathyroids are involved, the diagnosis should be qualified as bilateral.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0282.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0280.jpg

整理：北京天融慧通科技有限责任公司（LabSmart）｜ https://www.labsmart.cn