# 矿化(Mineralization) - 器官 / 系统:前列腺 / 雄性生殖系统(prostate / reproductive-system-male) - NTP 数据编号:ntp-0446 - 规范 URL:https://www.labsmart.cn/ntp/prostate-mineralization.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#prostate-mineralization - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/prostate/Mineralization - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 矿化(mineralization)的特征是局灶性(focal)至弥漫性(diffuse)的嗜碱性、各向异性、不规则颗粒状物质蓄积,可累及腺泡(Figure 1、Figure 2)或血管壁。 ## 病变描述(中文) 矿化(mineralization)的特征是局灶性(focal)至弥漫性(diffuse)的嗜碱性、各向异性、不规则颗粒状物质蓄积,可累及腺泡(Figure 1、Figure 2)或血管壁。此种程度的矿化不常见。可能发生两种类型的矿化:转移性(metastatic,与血钙水平升高相关的正常组织钙化)或营养不良性(dystrophic,与血钙水平升高无关的异常或退化组织中的矿物质沉积)。 ## 诊断与分级建议(NTP 共识,中文) 在前列腺的组织病理学评价中,应诊断矿化并给出严重程度分级。如有可能,应确定受累的叶,并在组织标识中注明。如果成对的叶均受累,诊断应注明为双侧性,严重程度以受累较重的叶为准。 ## 英文原文 · Comment Mineralization is characterized by focal to diffuse accumulation of basophilic, anisotropic, irregular granular material that may involve the glandular acini ( Figure 1 and Figure 2 ) or vessel wall. This degree of mineralization is unusual. Two types of mineralization may occur: metastatic (calcification of normal tissue associated with high blood levels of calcium) or dystrophic (mineral deposits in abnormal or degenerating tissue not associated with increased blood levels of calcium). ## 英文原文 · Recommendation Mineralization should be diagnosed during histopathologic evaluation of prostate and given a severity grade. The affected lobe(s) should be identified if possible and indicated in the tissue identification. If paired lobes are affected, the diagnosis should be indicated as bilateral and the degree of severity based on more severely affected lobe. ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_0795.jpg - https://www.labsmart.cn/ntp-atlas-images/ntp_0790.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn