# 矿化（Mineralization）

- 器官 / 系统：精囊 / 雄性生殖系统（seminal-vesicle / reproductive-system-male）
- NTP 数据编号：ntp-0484
- 规范 URL：https://www.labsmart.cn/ntp/seminal-vesicle-mineralization.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#seminal-vesicle-mineralization
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/seminal-vesicle/Mineralization
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
矿化（mineralization）由不规则无定形嗜碱性物质沉积构成（Figure 1、Figure 2、Figure 3）。

## 病变描述（中文）
矿化（mineralization）由不规则无定形嗜碱性物质沉积构成（Figure 1、Figure 2、Figure 3）。它可以是 局灶性（focal） 或 多灶性（multifocal）（箭头，Figure 1、Figure 2）。矿化在精囊中不常见，很可能是与化学处理无关的偶然发现。转移性矿化（metastatic mineralization）发生于正常组织，与血钙水平升高相关。营养不良性矿物质沉积（dystrophic mineral deposits）发生于异常组织，与血钙水平升高无关。在 Figure 1、Figure 2、Figure 3 中，精囊萎缩并伴有结缔组织增多，表明该矿化很可能是营养不良性的。

## 诊断与分级建议（NTP 共识，中文）
矿化应当被诊断并给出严重程度分级。如果双侧精囊均受累，诊断应当限定为双侧性，严重程度分级应当基于受累更严重的精囊。

## 英文原文 · Comment
Mineralization consists of deposition of irregular amorphous basophilic material ( Figure 1 , Figure 2 , and Figure 3 ). It can be focal or multifocal (arrows, Figure 1 and Figure 2 ). Mineralization is uncommon in the seminal vesicle and is likely an incidental finding not associated with chemical treatment. Metastatic mineralization occurs in normal tissues and is associated with elevated blood calcium levels. Dystrophic mineral deposits occur in abnormal tissues and are not associated with elevated blood calcium levels. In Figure 1 , Figure 2 , and Figure 3 , the seminal vesicle is atrophic with increased connective tissue, indicating that the mineralization is probably dystrophic.

## 英文原文 · Recommendation
Mineralization should be diagnosed and given a severity grade. If both seminal vesicles are involved, the diagnosis should be qualified as bilateral, and the severity grade should be based on the more severely affect seminal vesicle.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0800.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0804.jpg

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