# 异物（Foreign Body）

- 器官 / 系统：前胃 / 消化系统（stomach-forestomach / alimentary-system）
- NTP 数据编号：ntp-0210
- 规范 URL：https://www.labsmart.cn/ntp/stomach-forestomach-foreign-body.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#stomach-forestomach-foreign-body
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-forestomach/ForeignBody
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
毛发或饲料物质可继发于灌胃操作造成的损伤或外源性化学物引起的溃疡，嵌入前胃壁内。

## 病变描述（中文）
毛发或饲料物质可继发于灌胃操作造成的损伤或外源性化学物引起的溃疡，嵌入前胃壁内。在 Figure 1、Figure 2 中，黏膜下层可见一个中央含有毛干（箭头）的小型肉芽肿；其上方黏膜已从先前损伤中愈合。这被认为是对照动物中的一个小型偶发性病变，可能继发于先前的灌胃创伤。

## 诊断与分级建议（NTP 共识，中文）
原发性异物应当诊断，但不进行分级。如果异物引起显著的炎症反应，则异物和炎症均予诊断。诸如毛发或饲料物质等被被动推入溃疡区域的异物，不应单独诊断，但可在叙述中描述。

## 英文原文 · Comment
Hair or feed material can become embedded in the wall of the forestomach secondary to injury from a gavage procedure or ulceration from xenobiotics. In Figure 1 and Figure 2 , a small granuloma with a central hair shaft (arrow) is in the submucosa; the overlying mucosa has healed from a previous injury. This is considered a small incidental lesion in a control animal that may have occurred secondary to previous gavage trauma.

## 英文原文 · Recommendation
A primary foreign body should be diagnosed but not graded. If a foreign body causes a significant inflammatory response, then both the foreign body and inflammation are diagnosed. A foreign body such as hairs or feed material that has been passively pushed into an ulcerated area should not be diagnosed separately but can be described in the narrative.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0091.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0095.jpg

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