# 异物（Foreignbody）

- 器官 / 系统：腺胃 / 消化系统（stomach-glandular-stomach / alimentary-system）
- NTP 数据编号：ntp-0270
- 规范 URL：https://www.labsmart.cn/ntp/stomach-glandular-stomach-foreignbody.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#stomach-glandular-stomach-foreignbody
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/Foreignbody
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
毛发（Figure 1、Figure 2，箭头）或饲料物质可继发于灌胃操作所致的损伤或外源性化学物所致的溃疡形成而嵌入腺胃壁。

## 病变描述（中文）
毛发（Figure 1、Figure 2，箭头）或饲料物质可继发于灌胃操作所致的损伤或外源性化学物所致的溃疡形成而嵌入腺胃壁。溃疡形成过程使下方的固有层和肌层暴露于胃内容物，并使毛发和食物物质得以穿透进入溃疡下方形成的肉芽组织。

## 诊断与分级建议（NTP 共识，中文）
原发性异物应当诊断，但不进行分级。如果异物引起了显著的炎症反应，则异物和炎症两者均予诊断。在上述所示病例中，异物（毛发）和炎症（肉芽肿性）两者均应诊断。诸如毛发或饲料物质等被动附着于溃疡表面的异物不应单独诊断；可在叙述中描述。

## 英文原文 · Comment
Hair ( Figure 1 and Figure 2 , arrows) or feed material can become embedded in the wall of the glandular stomach secondary to injury from a gavage procedure or ulceration from xenobiotics. The process of ulceration exposes the underlying propria and muscular wall to gastric contents and allows hair and food material to penetrate into the granulation tissue, which forms beneath the ulcer.

## 英文原文 · Recommendation
A primary foreign body should be diagnosed but not graded. If a foreign body causing a significant inflammatory response, then both the foreign body and inflammation are diagnosed. In the case illustrated above, both the foreign body (hair) and the inflammation (granulomatous) should be diagnosed. A foreign body such as hair or feed material that is passively adhered to an ulcerated surface should not be diagnosed separately; it can be described in the narrative.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0138.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0133.jpg

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