鳞状化生Metaplasia Squamous · 腺胃 · 消化系统 · NTP ntp-0287
诊断要点：无论何时出现，鳞状化生均应予以诊断，并根据化生区域的数量和大小进行分级。相关病变（如炎症）应单独诊断。
病变描述
腺胃鳞状化生（squamous metaplasia）的特征是一种可逆性改变，即立方状或柱状黏膜上皮细胞被鳞状上皮细胞所取代（Figure 1、Figure 2，箭头）。鳞状化生常常（但并非总是）是对抗不良环境条件（如慢性刺激）的一种适应性改变，若去除病因则可逆转。腺胃鳞状化生最常发生于界限嵴（limiting ridge）（Figure 1、Figure 2，箭头）。它可以是偶然性发现，也可以是治疗相关病变。
诊断与分级建议（NTP 共识）
无论何时出现，鳞状化生均应予以诊断，并根据化生区域的数量和大小进行分级。相关病变（如炎症）应单独诊断。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Squamous metaplasia of the glandular stomach is characterized by a reversible change in which cuboidal or columnar mucosal epithelial cells are replaced by squamous epithelial cells ( Figure 1 and Figure 2 , arrows). Squamous metaplasia is often but not always an adaptive change to withstand adverse environmental conditions, such as chronic irritation, and is reversible if the cause is removed. Squamous metaplasia of the glandular stomach most often occurs at the limiting ridge ( Figure 1 and Figure 2 , arrows). It can be an incidental finding or a treatment-related lesion.
Recommendation：
Whenever present, squamous metaplasia should be diagnosed and graded based on the number and size of metaplastic areas. Associated lesions, such as inflammation, should be diagnosed separately.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/MetaplasiaSquamous
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Metaplasia Squamous (stomach-glandular-stomach). LabSmart 中文版：
https://www.labsmart.cn/ntp/stomach-glandular-stomach-metaplasia-squamous.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#stomach-glandular-stomach-metaplasia-squamous