# 鳞状化生（Metaplasia Squamous）

- 器官 / 系统：腺胃 / 消化系统（stomach-glandular-stomach / alimentary-system）
- NTP 数据编号：ntp-0287
- 规范 URL：https://www.labsmart.cn/ntp/stomach-glandular-stomach-metaplasia-squamous.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#stomach-glandular-stomach-metaplasia-squamous
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/MetaplasiaSquamous
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
腺胃鳞状化生（squamous metaplasia）的特征是一种可逆性改变，即立方状或柱状黏膜上皮细胞被鳞状上皮细胞所取代（Figure 1、Figure 2，箭头）。

## 病变描述（中文）
腺胃鳞状化生（squamous metaplasia）的特征是一种可逆性改变，即立方状或柱状黏膜上皮细胞被鳞状上皮细胞所取代（Figure 1、Figure 2，箭头）。鳞状化生常常（但并非总是）是对抗不良环境条件（如慢性刺激）的一种适应性改变，若去除病因则可逆转。腺胃鳞状化生最常发生于界限嵴（limiting ridge）（Figure 1、Figure 2，箭头）。它可以是偶然性发现，也可以是治疗相关病变。

## 诊断与分级建议（NTP 共识，中文）
无论何时出现，鳞状化生均应予以诊断，并根据化生区域的数量和大小进行分级。相关病变（如炎症）应单独诊断。

## 英文原文 · Comment
Squamous metaplasia of the glandular stomach is characterized by a reversible change in which cuboidal or columnar mucosal epithelial cells are replaced by squamous epithelial cells ( Figure 1 and Figure 2 , arrows). Squamous metaplasia is often but not always an adaptive change to withstand adverse environmental conditions, such as chronic irritation, and is reversible if the cause is removed. Squamous metaplasia of the glandular stomach most often occurs at the limiting ridge ( Figure 1 and Figure 2 , arrows). It can be an incidental finding or a treatment-related lesion.

## 英文原文 · Recommendation
Whenever present, squamous metaplasia should be diagnosed and graded based on the number and size of metaplastic areas. Associated lesions, such as inflammation, should be diagnosed separately.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0146.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0150.jpg

整理：北京天融慧通科技有限责任公司（LabSmart）｜ https://www.labsmart.cn