# 间质细胞合体细胞（Interstitial Cell Syncytial Cells）

- 器官 / 系统：睾丸 / 雄性生殖系统（testis / reproductive-system-male）
- NTP 数据编号：ntp-0476
- 规范 URL：https://www.labsmart.cn/ntp/testis-interstitial-cell-syncytial-cells.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#testis-interstitial-cell-syncytial-cells
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/InterstitialCell-SyncytialCells
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
合胞体细胞形成并不常见，文献中尚未见描述。间质合胞体细胞可能代表 Leydig 细胞或巨噬细胞。

## 病变描述（中文）
合胞体细胞形成并不常见，文献中尚未见描述。间质合胞体细胞可能代表 Leydig 细胞或巨噬细胞。可使用 Periodic acid-Schiff 染色加以区分，该染色可使巨噬细胞着色，但不使 Leydig 细胞着色。该病变的发病机制及意义尚不明确。

## 诊断与分级建议（NTP 共识，中文）
间质合胞体细胞存在时应作出诊断并分级；若其发生率及/或严重程度似乎与受试物给药相关，则应在病理学叙述中加以讨论。存在双侧病变时，诊断应注明双侧性。分页 图1，共2页 下一页 › 睾丸，间质细胞 - 空泡化，见于一只慢性研究中的雄性 FVB/N 转基因小鼠。可见间质合胞体细胞（箭头）。放大图像 所有图像 放大所有图像 睾丸，间质细胞 - 空泡化，见于一只慢性研究中的雄性 FVB/N 转基因小鼠。可见间质合胞体细胞（箭头）。"> 睾丸，间质细胞 - 空泡化，见于一只慢性研究中的雄性 FVB/N 转基因小鼠。可见间质合胞体细胞（箭头）。" /> 睾丸，间质细胞 - 空泡化，见于一只慢性研究中的雄性 FVB/N 转基因小鼠。可见间质合胞体细胞（箭头）。睾丸，间质细胞 - 空泡化，见于一只慢性研究中的雄性 FVB/N 转基因小鼠。可见间质合胞体细胞（箭头），并伴有 Leydig 细胞空泡化。"> 睾丸，间质细胞 - 空泡化，见于一只慢性研究中的雄性 FVB/N 转基因小鼠。可见间质合胞体细胞（箭头），并伴有 Leydig 细胞空泡化。" /> 睾丸，间质细胞 - 空泡化，见于一只慢性研究中的雄性 FVB/N 转基因小鼠。可见间质合胞体细胞（箭头），并伴有 Leydig 细胞空泡化。

## 英文原文 · Comment
The syncytial cell formation is unusual and has not been described in the literature. The interstitial syncytial cells may represent Leydig cells or macrophages. These can be distinguished using a Periodic acid-Schiff stain, which stains macrophages but not Leydig cells. The pathogenesis and significance of this lesion are unknown.

## 英文原文 · Recommendation
Interstitial syncytial cells should be diagnosed and graded when present and should be discussed in the pathology narrative if the incidence and/or severity appears to be related to chemical administration. Diagnosis should indicate bilaterality when present. Pagination Figure 1 of 2 Next page › Testis, Interstitial cell - Vacuolation in a male FVB/N transgenic mouse from a chronic study. There are interstitial syncytial cells (arrows). Enlarge Image All Images Enlarge All Images Testis, Interstitial cell - Vacuolation in a male FVB/N transgenic mouse from a chronic study. There are interstitial syncytial cells (arrows). "> Testis, Interstitial cell - Vacuolation in a male FVB/N transgenic mouse from a chronic study. There are interstitial syncytial cells (arrows). " /> Testis, Interstitial cell - Vacuolation in a male FVB/N transgenic mouse from a chronic study. There are interstitial syncytial cells (arrows). Testis, Interstitial cell - Vacuolation in a male FVB/N transgenic mouse from a chronic study. There are interstitial syncytial cells (arrows) accompanied by vacuolation of Leydig cells. "> Testis, Interstitial cell - Vacuolation in a male FVB/N transgenic mouse from a chronic study. There are interstitial syncytial cells (arrows) accompanied by vacuolation of Leydig cells. " /> Testis, Interstitial cell - Vacuolation in a male FVB/N transgenic mouse from a chronic study. There are interstitial syncytial cells (arrows) accompanied by vacuolation of Leydig cells.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0817.jpg
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