# 精子肉芽肿（Sperm Granuloma）

- 器官 / 系统：睾丸 / 雄性生殖系统（testis / reproductive-system-male）
- NTP 数据编号：ntp-0472
- 规范 URL：https://www.labsmart.cn/ntp/testis-sperm-granuloma.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#testis-sperm-granuloma
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/SpermGranuloma
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
精子肉芽肿（sperm granuloma）在睾丸中不常见；在附睾中则常见得多。

## 病变描述（中文）
精子肉芽肿（sperm granuloma）在睾丸中不常见；在附睾中则常见得多。它们最常作为曲细精管或睾丸网内精子淤滞的继发结果出现。精子肉芽肿可进展为血-睾屏障的破坏，并使受累的生精小管被肉芽肿性炎症所取代。这最常见表现为偶然发现的背景性病变。

## 诊断与分级建议（NTP 共识，中文）
精子肉芽肿只要存在就应诊断。不必对精子肉芽肿进行分级，除非病理学家认为分级有助于将该病变识别为与处理相关。相关病变，如变性，应单独诊断。分页 图1，共1张 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠，但其在小鼠或大鼠中的表现相同。放大图像 所有图像 放大所有图像 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠，但其在小鼠或大鼠中的表现相同。"> 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠，但其在小鼠或大鼠中的表现相同。" /> 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠，但其在小鼠或大鼠中的表现相同。

## 英文原文 · Comment
Sperm granulomas are uncommon findings in the testis; they are much more common in the epididymis. They most often occur as a sequel to sperm stasis within a tubule or within the rete testis. Sperm granulomas may progress to disruption of the blood-testis barrier and replacement of the affected seminiferous tubule with granulomatous inflammation. This is most commonly seen as an incidental background lesion.

## 英文原文 · Recommendation
Sperm granulomas should be diagnosed whenever present. It is not necessary to grade sperm granulomas, unless the pathologist feels that grading would help identify the lesion as being treatment-related. Associated lesions, such as degeneration, should be diagnosed separately. Pagination Figure 1 of 1 Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same. Enlarge Image All Images Enlarge All Images Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same. "> Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same. " /> Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0841.jpg

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