# 矿化(Mineralization) - 器官 / 系统:胸腺 / 免疫系统(thymus / immune-system) - NTP 数据编号:ntp-0025 - 规范 URL:https://www.labsmart.cn/ntp/thymus-mineralization.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#thymus-mineralization - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/immune-system/thymus/Mineralization - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 矿化通常不作为胸腺的原发性病变发生。然而,它可继发于肾脏和/或甲状旁腺疾病(转移性矿化),或伴随胸腺坏死(营养不良性矿化)发生。 ## 病变描述(中文) 矿化通常不作为胸腺的原发性病变发生。然而,它可继发于肾脏和/或甲状旁腺疾病(转移性矿化),或伴随胸腺坏死(营养不良性矿化)发生。该病变的特征是数量不等的深嗜碱性、无定形和/或颗粒状物质(Figure 1、Figure 2,箭头)。在肾脏或甲状旁腺疾病时,矿物质可作为多灶性(multifocal)病变发生于胸腺内,也可发生于坏死灶内。 ## 诊断与分级建议(NTP 共识,中文) 与肾脏和/或甲状旁腺疾病相关的胸腺矿化应当诊断并分级。与胸腺坏死相关的矿化不应单独诊断,除非其严重程度足以支持单独诊断,但应在病理描述中予以描述。 ## 英文原文 · Comment Mineralization does not typically occur as a primary lesion in the thymus. However, it can occur secondary to renal and/or parathyroid disease (metastatic mineralization) or with thymic necrosis (dystrophic mineralization). This lesion is characterized by variable amounts of densely basophilic, amorphous, and/or granular material ( Figure 1 and Figure 2 , arrows). Mineral may occur as multifocal lesions within the thymus with renal or parathyroid disease or may occur within necrotic foci. ## 英文原文 · Recommendation Thymic mineralization should be diagnosed and graded if associated with renal and/or parathyroid disease. Mineralization associated with thymic necrosis should not be diagnosed separately unless warranted by severity, but should be described in the pathology narrative. ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_0469.jpg - https://www.labsmart.cn/ntp-atlas-images/ntp_0470.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn