# 滤泡扩张（Follicle Dilation）

- 器官 / 系统：甲状腺 / 内分泌系统（thyroid-gland / endocrine-system）
- NTP 数据编号：ntp-0064
- 规范 URL：https://www.labsmart.cn/ntp/thyroid-gland-follicle-dilation.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#thyroid-gland-follicle-dilation
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/thyroid-gland/Follicle-Dilation
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
一个或多个扩张的滤泡是小鼠和大鼠甲状腺中常见的、与年龄相关的改变。受累滤泡的胶质可呈淡染（Figure 1、Figure 2）或缺失，管腔内可见脱落细胞。

## 病变描述（中文）
一个或多个扩张的滤泡是小鼠和大鼠甲状腺中常见的、与年龄相关的改变。受累滤泡的胶质可呈淡染（Figure 1、Figure 2）或缺失，管腔内可见脱落细胞。扩张的滤泡常见于甲状腺外周（Figure 3、Figure 4）。扩张的滤泡衬以低立方至扁平上皮。

## 诊断与分级建议（NTP 共识，中文）
推荐对扩张滤泡进行记录和分级。诊断应指明扩张是否为双侧性，严重程度分级应基于受累更严重的甲状腺。扩张滤泡管腔内出现细胞无需单独诊断，除非其严重程度足以需要单独诊断。

## 英文原文 · Comment
One or more dilated follicles occur as a common and age-associated change in mouse and rat thyroids. Affected follicles may have pale ( Figure 1 and Figure 2 ) or absent colloid, and exfoliated cells may be present in the lumen. The dilated follicles are frequently seen at the periphery of the thyroid gland ( Figure 3 and Figure 4 ). Dilated follicles are lined by low cuboidal to flattened epithelium.

## 英文原文 · Recommendation
Documentation and grading of dilated follicles are recommended. The diagnosis should indicate whether the dilation is bilateral, with a severity grade based on the more severely affected thyroid gland. The presence of cells within the lumens of the dilated follicles need not be diagnosed separately unless warranted by severity.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0296.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0298.jpg

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