# 化生(Metaplasia) - 器官 / 系统:膀胱 / 泌尿系统(urinary-bladder / urinary-system) - NTP 数据编号:ntp-0187 - 规范 URL:https://www.labsmart.cn/ntp/urinary-bladder-metaplasia.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#urinary-bladder-metaplasia - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/urinary-bladder/Metaplasia - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 尿路上皮化生(metaplasia)反映了尿路上皮在多种条件下发生化生性改变的能力。 ## 病变描述(中文) 尿路上皮化生(metaplasia)反映了尿路上皮在多种条件下发生化生性改变的能力。鳞状化生(squamous metaplasia),伴或不伴角化,是最常见的变异型(Figure 1、Figure 2、Figure 3)。黏液性、腺性或混合性化生性病变较少见(Figure 4)。 ## 诊断与分级建议(NTP 共识,中文) 尿路上皮化生,特别是化生的类型,当它成为病变的主要部分时,例如与炎症或增生相关时,应当诊断并给出严重程度分级。当小病变或局灶性(focal)病变是原发性病变(如慢性炎症和/或增生)的一部分时,不应单独诊断。 ## 英文原文 · Comment Metaplasia of the urothelium reflects the potential of the urothelium to undergo a metaplastic change under a variety of conditions. Squamous metaplasia, with or without keratinization, is the most common variant observed ( Figure 1 , Figure 2 , and Figure 3 ). Mucinous, glandular, or mixtures of metaplastic lesions are less commonly observed ( Figure 4 ). ## 英文原文 · Recommendation Urothelial metaplasia and, in particular, the type of metaplasia should be diagnosed and given a severity grade when it becomes a major part of a lesion, for instance, in association with inflammation or hyperplasia. Small or focal lesions, when part of a primary lesion such as chronic inflammation and/or hyperplasia, should not be diagnosed separately. ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_1135.jpg - https://www.labsmart.cn/ntp-atlas-images/ntp_1134.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn