# 细胞质空泡化(Vacuolation Cytoplasmic) - 器官 / 系统:膀胱 / 泌尿系统(urinary-bladder / urinary-system) - NTP 数据编号:ntp-0197 - 规范 URL:https://www.labsmart.cn/ntp/urinary-bladder-vacuolation-cytoplasmic.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#urinary-bladder-vacuolation-cytoplasmic - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/urinary-bladder/VacuolationCytoplasmic - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 尿路上皮细胞的细胞质空泡化被视为一种非特异性病变,可能继发于多种膀胱毒物或致癌物所致的细胞损伤。 ## 病变描述(中文) 尿路上皮细胞的细胞质空泡化被视为一种非特异性病变,可能继发于多种膀胱毒物或致癌物所致的细胞损伤。它可能与变性有关,也可能无关。空泡化通常见于“伞”细胞或更表浅的尿路上皮细胞(Figure 1、Figure 2)。均匀一致的尿路上皮细胞空泡化(通常位于基底细胞层内)可能是自溶所致的伪影(Figure 3)。 ## 诊断与分级建议(NTP 共识,中文) 细胞质空泡化应当被诊断并给出严重程度分级。 ## 英文原文 · Comment Cytoplasmic vacuolation of urothelial cells is regarded as a nonspecific lesion that may occur secondary to cell injury by a variety of bladder toxicants or carcinogens. It may or may not be related to degeneration. Vacuolation is usually noted in “umbrella” cells or more superficial urothelial cells ( Figure 1 and Figure 2 ). Uniform urothelial cell vacuolation (typically within the basal cell layer) may be an artifact resulting from autolysis ( Figure 3 ). ## 英文原文 · Recommendation Cytoplasmic vacuolation should be diagnosed and given a severity grade. ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_1152.jpg - https://www.labsmart.cn/ntp-atlas-images/ntp_1151.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn