# 淀粉样物质(Amyloid) - 器官 / 系统:子宫 / 雌性生殖系统(uterus / reproductive-system-female) - NTP 数据编号:ntp-0537 - 规范 URL:https://www.labsmart.cn/ntp/uterus-amyloid.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#uterus-amyloid - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/Amyloid - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 淀粉样物质(amyloid)是一种无定形、嗜酸性、淡染的物质,在小鼠子宫内膜和子宫肌层的间质中偶见(Figure 1、Figure 2)。 ## 病变描述(中文) 淀粉样物质(amyloid)是一种无定形、嗜酸性、淡染的物质,在小鼠子宫内膜和子宫肌层的间质中偶见(Figure 1、Figure 2)。严重病例中,它会导致子宫增厚和硬度增加。子宫内淀粉样物质的存在可能反映动物体内其他部位的淀粉样物质沉积,主要位于中等大小动脉的外膜。淀粉样物质沉积必须与其他纤维蛋白样变化相鉴别:纤维化、水肿和纤维蛋白。 ## 诊断与分级建议(NTP 共识,中文) 子宫——淀粉样物质一旦出现即应诊断并分级。继发性病变,如驻留细胞的变性或坏死,除非严重程度确有必要,否则不应单独诊断。如果淀粉样物质沉积可能影响研究的解释,则应在病理学叙述中加以讨论。 ## 英文原文 · Comment Amyloid, an amorphous, eosinophilic, pale-staining material, is infrequently seen in mice in the stroma of the endometrium and myometrium ( Figure 1 and Figure 2 ). In severe cases, it causes thickening and increased firmness of the uterus. The presence of amyloid in the uterus may reflect amyloid deposition elsewhere in the animal, principally in the adventitia of medium-size arteries. Amyloid deposition must be differentiated from other fibrinoid changes: fibrosis, edema, and fibrin. ## 英文原文 · Recommendation Uterus - Amyloid should be diagnosed and graded whenever present. Secondary lesions such as degeneration or necrosis of resident cells should not be diagnosed separately unless warranted by severity. If the amyloid deposition may affect the interpretation of the study, it should be discussed in the pathology narrative. ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_0661.jpg - https://www.labsmart.cn/ntp-atlas-images/ntp_0662.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn