# 坏死(Necrosis) - 器官 / 系统:子宫 / 雌性生殖系统(uterus / reproductive-system-female) - NTP 数据编号:ntp-0529 - 规范 URL:https://www.labsmart.cn/ntp/uterus-necrosis.html - 中文图谱总页锚点:https://www.labsmart.cn/ntp-atlas.html#uterus-necrosis - 原始出处:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/Necrosis - 授权:美国联邦政府作品,公有领域;引用请标注 NTP Nonneoplastic Lesion Atlas - 适用说明:仅供科研使用,不用于临床诊断 ## 一句话结论 子宫坏死(uterine necrosis)较为罕见,但其组织学表现与其他部位的坏死相似,初期表现为组织中的细胞死亡,特征为核固缩(nuclear pyknosis)和/或核碎裂(karyorrhexis)、胞质嗜酸性(cytoplasmic eosinophilia)以及细胞肿胀或皱缩。 ## 病变描述(中文) 子宫坏死(uterine necrosis)较为罕见,但其组织学表现与其他部位的坏死相似,初期表现为组织中的细胞死亡,特征为核固缩(nuclear pyknosis)和/或核碎裂(karyorrhexis)、胞质嗜酸性(cytoplasmic eosinophilia)以及细胞肿胀或皱缩。坏死的后果是肉芽组织(granulation tissue)和矿化(mineralization)(Figure 1、Figure 2)。子宫坏死可能由相关的动脉炎(arteritis)或血栓形成(thrombosis)及随后的组织梗死(infarction)引起(Figure 1、Figure 2)。 ## 诊断与分级建议(NTP 共识,中文) 子宫-坏死(Uterus - Necrosis)应予以诊断并分级。如果坏死继发于其他病变,如炎症(inflammation),则不应单独诊断,除非其严重程度足以支持单独诊断。继发于坏死的病变,如炎症或出血(hemorrhage),不应单独诊断,除非其严重程度足以支持单独诊断。如果病理学家认为该坏死代表梗死(infarct),应在病理学描述(pathology narrative)中注明。 ## 英文原文 · Comment Uterine necrosis is rarely encountered, but the histology of the lesion is like necrosis elsewhere, with cell death in the tissue characterized by nuclear pyknosis and/or karyorrhexis, cytoplasmic eosinophilia, and cellular swelling or shrinkage initially. The consequence of necrosis is granulation tissue and mineralization ( Figure 1 and Figure 2 ). Uterine necrosis may occur due to associated arteritis or thrombosis and subsequent infarction of the tissue ( Figure 1 and Figure 2 ). ## 英文原文 · Recommendation Uterus - Necrosis should be diagnosed and graded. If the necrosis is secondary to another lesion, such as inflammation, it should not be diagnosed separately unless warranted by severity. Lesions secondary to necrosis, such as inflammation or hemorrhage, should not be diagnosed separately unless warranted by severity. The pathologist should note in the pathology narrative if the necrosis is thought to represent an infarct. ## 配图 - https://www.labsmart.cn/ntp-atlas-images/ntp_0686.jpg - https://www.labsmart.cn/ntp-atlas-images/ntp_0692.jpg 整理:北京天融慧通科技有限责任公司(LabSmart)| https://www.labsmart.cn