# 血栓（Thrombus）

- 器官 / 系统：子宫 / 雌性生殖系统（uterus / reproductive-system-female）
- NTP 数据编号：ntp-0543
- 规范 URL：https://www.labsmart.cn/ntp/uterus-thrombus.html
- 中文图谱总页锚点：https://www.labsmart.cn/ntp-atlas.html#uterus-thrombus
- 原始出处：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/Thrombus
- 授权：美国联邦政府作品，公有领域；引用请标注 NTP Nonneoplastic Lesion Atlas
- 适用说明：仅供科研使用，不用于临床诊断

## 一句话结论
大或小的血栓可能阻塞小鼠子宫血管（Figure 1、Figure 2）。由于坏死或碎屑遮蔽，可能观察不到清晰的内皮衬里。

## 病变描述（中文）
大或小的血栓可能阻塞小鼠子宫血管（Figure 1、Figure 2）。由于坏死或碎屑遮蔽，可能观察不到清晰的内皮衬里。这可能伴有周围血管的突出和扩张（angiectasis）。血栓必须与血管瘤和血管肉瘤相鉴别。血管扩张的特征是血管衬以单纯的非肥厚性内皮衬里，且常与血栓形成同时出现。血管瘤和血管肉瘤具有丰满的衬里内皮细胞。血管肉瘤的内皮细胞表现出间变和核分裂率增加。

## 诊断与分级建议（NTP 共识，中文）
子宫——血栓形成（thrombosis）应被诊断，但无需分级。继发于另一过程（肿瘤）的血栓不应被诊断。由血栓引起的坏死应单独诊断和分级。

## 英文原文 · Comment
Large or small thrombi may occlude uterine blood vessels in mice ( Figure 1 and Figure 2 ). A distinct endothelial lining may not be observed due to necrosis or obscuring by detritus. This may be associated with prominence and dilation of the surrounding blood vessels (angiectasis). Thrombi must be differentiated from hemangioma and hemangiosarcoma. Angiectasis is characterized by blood vessels lined by a simple nonhypertrophic endothelial lining and is frequently seen with thrombosis. Hemangioma and hemangiosarcoma have plump lining endothelial cells. The endothelial cells of hemangiosarcoma exhibit anaplasia and an increased rate of mitoses.

## 英文原文 · Recommendation
Uterus - Thrombosis should be diagnosed but need not be graded. Thrombi that are secondary to another process (a neoplasm) should not be diagnosed. Necrosis that is caused by a thrombus should be diagnosed and graded separately.

## 配图
- https://www.labsmart.cn/ntp-atlas-images/ntp_0689.jpg
- https://www.labsmart.cn/ntp-atlas-images/ntp_0694.jpg

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