坏死Necrosis · 输卵管 · 雌性生殖系统 · NTP ntp-0546
诊断要点：输卵管-坏死（Oviduct - Necrosis）一旦出现即应诊断并分级。继发性病变如炎症或出血，除非严重程度足以需要诊断，否则不应诊断。
病变描述
输卵管坏死（Oviduct necrosis）在啮齿类动物研究中罕见。它可能是邻近卵巢或子宫相关炎症性改变的结果。输卵管坏死的特征为上皮细胞嗜酸性增强、离散、碎裂和脱落（Figure 1、Figure 2）。细胞核固缩和核碎裂。通常伴有炎症细胞浸润。
诊断与分级建议（NTP 共识）
输卵管-坏死（Oviduct - Necrosis）一旦出现即应诊断并分级。继发性病变如炎症或出血，除非严重程度足以需要诊断，否则不应诊断。如果坏死继发于其他病变，如炎症，除非严重程度足以需要诊断，否则不应诊断。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Oviduct necrosis is rarely seen in rodent studies. It may be a result of an associated inflammatory change in the adjacent ovary or uterus. Oviduct necrosis is characterized by hypereosinophilic, dissociated, fragmented, and sloughed epithelial cells ( Figure 1 and Figure 2 ). Nuclei are pyknotic and karyorrhectic. It is usually accompanied by an inflammatory infiltrate.
Recommendation：
Oviduct - Necrosis should be diagnosed and graded whenever present. Secondary lesions such as inflammation or hemorrhage should not be diagnosed unless warranted by severity. If the necrosis is secondary to another lesion, such as inflammation, it should not be diagnosed unless warranted by severity.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/oviduct/Necrosis
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Necrosis (oviduct). LabSmart 中文版：
https://www.labsmart.cn/ntp/oviduct-necrosis.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#oviduct-necrosis