矿化Mineralization · 精囊 · 雄性生殖系统 · NTP ntp-0484
诊断要点：矿化应当被诊断并给出严重程度分级。如果双侧精囊均受累，诊断应当限定为双侧性，严重程度分级应当基于受累更严重的精囊。
病变描述
矿化（mineralization）由不规则无定形嗜碱性物质沉积构成（Figure 1、Figure 2、Figure 3）。它可以是 局灶性（focal） 或 多灶性（multifocal）（箭头，Figure 1、Figure 2）。矿化在精囊中不常见，很可能是与化学处理无关的偶然发现。转移性矿化（metastatic mineralization）发生于正常组织，与血钙水平升高相关。营养不良性矿物质沉积（dystrophic mineral deposits）发生于异常组织，与血钙水平升高无关。在 Figure 1、Figure 2、Figure 3 中，精囊萎缩并伴有结缔组织增多，表明该矿化很可能是营养不良性的。
诊断与分级建议（NTP 共识）
矿化应当被诊断并给出严重程度分级。如果双侧精囊均受累，诊断应当限定为双侧性，严重程度分级应当基于受累更严重的精囊。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Mineralization consists of deposition of irregular amorphous basophilic material ( Figure 1 , Figure 2 , and Figure 3 ). It can be focal or multifocal (arrows, Figure 1 and Figure 2 ). Mineralization is uncommon in the seminal vesicle and is likely an incidental finding not associated with chemical treatment. Metastatic mineralization occurs in normal tissues and is associated with elevated blood calcium levels. Dystrophic mineral deposits occur in abnormal tissues and are not associated with elevated blood calcium levels. In Figure 1 , Figure 2 , and Figure 3 , the seminal vesicle is atrophic with increased connective tissue, indicating that the mineralization is probably dystrophic.
Recommendation：
Mineralization should be diagnosed and given a severity grade. If both seminal vesicles are involved, the diagnosis should be qualified as bilateral, and the severity grade should be based on the more severely affect seminal vesicle.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/seminal-vesicle/Mineralization
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Mineralization (seminal-vesicle). LabSmart 中文版：
https://www.labsmart.cn/ntp/seminal-vesicle-mineralization.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#seminal-vesicle-mineralization