矿化Mineralization · 胸腺 · 免疫系统 · NTP ntp-0025
诊断要点:与肾脏和/或甲状旁腺疾病相关的胸腺矿化应当诊断并分级。与胸腺坏死相关的矿化不应单独诊断,除非其严重程度足以支持单独诊断,但应在病理描述中予以描述。
病变描述
矿化通常不作为胸腺的原发性病变发生。然而,它可继发于肾脏和/或甲状旁腺疾病(转移性矿化),或伴随胸腺坏死(营养不良性矿化)发生。该病变的特征是数量不等的深嗜碱性、无定形和/或颗粒状物质(Figure 1、Figure 2,箭头)。在肾脏或甲状旁腺疾病时,矿物质可作为多灶性(multifocal)病变发生于胸腺内,也可发生于坏死灶内。
诊断与分级建议(NTP 共识)
与肾脏和/或甲状旁腺疾病相关的胸腺矿化应当诊断并分级。与胸腺坏死相关的矿化不应单独诊断,除非其严重程度足以支持单独诊断,但应在病理描述中予以描述。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Mineralization does not typically occur as a primary lesion in the thymus. However, it can occur secondary to renal and/or parathyroid disease (metastatic mineralization) or with thymic necrosis (dystrophic mineralization). This lesion is characterized by variable amounts of densely basophilic, amorphous, and/or granular material ( Figure 1 and Figure 2 , arrows). Mineral may occur as multifocal lesions within the thymus with renal or parathyroid disease or may occur within necrotic foci.
Recommendation:
Thymic mineralization should be diagnosed and graded if associated with renal and/or parathyroid disease. Mineralization associated with thymic necrosis should not be diagnosed separately unless warranted by severity, but should be described in the pathology narrative.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/immune-system/thymus/Mineralization
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Mineralization (thymus). LabSmart 中文版:
https://www.labsmart.cn/ntp/thymus-mineralization.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#thymus-mineralization