牙本质嗜碱性颗粒Dentin Basophilic Granules · 牙齿 · 消化系统 · NTP ntp-0256
诊断要点:嗜碱性颗粒一旦出现即应诊断并分级。
病变描述
牙本质中的嗜碱性颗粒(Figure 1、Figure 2)在NTP研究中罕见。它们是小而圆的嗜碱性球状物,在牙本质层内呈线性排列。在暴露于氟化钠2年的F344大鼠的predentin和dentin中曾见到此类颗粒。据报道,类似的沉积物代表牙齿/骨骼标本脱钙过程中形成的氟化钙结晶。
诊断与分级建议(NTP 共识)
嗜碱性颗粒一旦出现即应诊断并分级。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Basophilic granules in the dentin ( Figure 1 and Figure 2 ) are rarely seen in the NTP studies. They are small, round, basophilic globules that occur in a linear pattern within the dentin layer. They have been seen in the predentin and dentin in F344 rats exposed to sodium fluoride for 2 years. Similar deposits are reported to represent calcium fluoride crystal formation that occurs during decalcification of tooth/bone specimens.
Recommendation:
Basophilic granules should be diagnosed and graded whenever present.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/tooth/Dentin-BasophilicGranules
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Dentin Basophilic Granules (tooth). LabSmart 中文版:
https://www.labsmart.cn/ntp/tooth-dentin-basophilic-granules.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#tooth-dentin-basophilic-granules