纤维化Fibrosis · 牙齿 · 消化系统 · NTP ntp-0261
诊断要点：当纤维化在病变中显著，或已进展至纤维化为唯一现存病变的程度时，应当对其进行诊断并分级。
病变描述
肺泡内的纤维化（Figure 1、Figure 2、Figure 3、Figure 4）可能是影响切牙或磨牙牙根的吸收所致。吸收可由错位咬合、感染或创伤（包括医源性骨折）引发。吸收可进展至牙齿完全缺失，并由纤维结缔组织和/或骨替代。炎症可伴随纤维化出现（Figure 3、Figure 4）。
诊断与分级建议（NTP 共识）
当纤维化在病变中显著，或已进展至纤维化为唯一现存病变的程度时，应当对其进行诊断并分级。若纤维化仅为炎症的次要成分，则不必单独诊断，但应在病理描述中予以描述。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Fibrosis within the alveolus ( Figure 1 , Figure 2 , Figure 3 , and Figure 4 ) may be the result of resorption affecting the incisor or molar roots. Resorption may be initiated by malocclusion, infection, or trauma (including iatrogenic fracture). Resorption may progress to complete loss of the tooth and replacement with fibrous connective tissue and/or bone. Inflammation may accompany the fibrosis ( Figure 3 and Figure 4 ).
Recommendation：
Fibrosis should be diagnosed and graded when it is prominent in a lesion or if it has progressed to the point that fibrosis is the only lesion present. If fibrosis is a minor component of inflammation, it is not necessary to diagnose it separately, though it should be described in the pathology narrative.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/tooth/Fibrosis
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Fibrosis (tooth). LabSmart 中文版：
https://www.labsmart.cn/ntp/tooth-fibrosis.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#tooth-fibrosis