牙周袋Periodontal Pocket · 牙齿 · 消化系统 · NTP ntp-0255

Comment：
Periodontal pockets ( Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 , and Figure 8 ) are common background findings in rodents. They are found in the periodontal tissues surrounding the teeth, especially the molars. The pockets represent an abnormally deepened gingival sulcus that is lined by keratinized squamous epithelium and are frequently secondary to the impaction of hair ( Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , and Figure 6 ), feed ( Figure 7 and Figure 8 ), or bedding material. Alternatively, bacterial periodontitis can result in detachment and resorption of periodontal ligament fibers and the formation of a periodontal pocket in which foreign bodies can become entrapped. Impacted hair, feed, or bedding may penetrate the surrounding tissues, resulting in chronic inflammation and fibrosis ( Figure 4 , Figure 5 , and Figure 6 ). They are lined by squamous epithelium that is often keratinized. Differential diagnoses for periodontal pocket include squamous cyst and cystic keratinizing hyperplasia. Cystic keratinizing hyperplasia is thought to be on a continuum from hyperplasia to squamous cell carcinoma. In comparison, periodontal pockets tend to be unilocular structures lined by normal squamous epithelium. Squamous cysts are similar to periodontal pockets morphologically, but they are not necessarily located adjacent to a tooth and do not communicate with the oral mucosa. Ideally, the communication to the oral cavity can be seen in a periodontal pocket lesion, but the opening may not be apparent because of the plane of section.

Recommendation：
Periodontal pockets should be diagnosed but not graded. Foreign material (e.g., hair shafts, bedding, feed) within the pocket should not be diagnosed separately but should be described in the pathology narrative. However, foreign material found in the tissue surrounding the pocket should be recorded as "foreign body." Associated inflammation and fibrosis should not be diagnosed separately unless warranted by severity.