导管扩张Duct Dilation · 附睾 · 雄性生殖系统 · NTP ntp-0496
诊断要点:应记录并对附睾管扩张进行分级;若其发生率或严重程度似乎与化学物给药相关,则应在病理学叙述中加以讨论。
病变描述
附睾管扩张是一种不常见的病变。附睾不同部位管腔直径差异显著,评估该病变时必须考虑这一点。该病变通常局限于附睾的特定节段。它可能与受试物相关(Figure 1、Figure 2),也可作为老年大鼠偶见的囊性背景病变出现。
诊断与分级建议(NTP 共识)
应记录并对附睾管扩张进行分级;若其发生率或严重程度似乎与化学物给药相关,则应在病理学叙述中加以讨论。若双侧附睾均受累,诊断应注明双侧性,并依据受累较重的一侧附睾确定严重程度。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Dilation of the epididymal ducts is an uncommon finding. The luminal diameter of the ducts varies significantly in different parts of the epididymis, and this must be taken into account when evaluating the change. The change is usually restricted to a specific segment of the epididymis. It can be test article related ( Figure 1 and Figure 2 ) or can be seen as an occasional cystic background finding in aging rats.
Recommendation:
Ductal dilation should be recorded and graded and should be discussed in the pathology narrative if the incidence and/or severity appears to be related to chemical administration. If both epididymides are involved, the diagnosis should indicate bilateral and severity based on the more severely affected epididymis.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/epididymis/Duct-Dilation
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Duct Dilation (epididymis). LabSmart 中文版:
https://www.labsmart.cn/ntp/epididymis-duct-dilation.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#epididymis-duct-dilation