扩张Dilation · 食管 · 消化系统 · NTP ntp-0304
诊断要点:食管扩张应当予以诊断,并根据扩张食管的整体大小进行分级。
病变描述
食管扩张(esophageal dilation)的特征是食管腔扩大和食管壁变薄。慢性食管扩张还可能伴有食管壁肌肉和神经细胞的退行性变。饲料物质嵌塞在食管内是食管扩张(扩张、巨食管)的原因之一。在 NTP 研究中,食管扩张主要发生于饲喂粉状饲料的雌性 F344 大鼠。该病变可导致死亡、化脓性异物性肺炎或鼻炎。
诊断与分级建议(NTP 共识)
食管扩张应当予以诊断,并根据扩张食管的整体大小进行分级。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Esophageal dilation is characterized by enlargement of the esophageal lumen and thinning of the esophageal wall. Chronic esophageal dilation may also have degeneration of the muscles and nerve cells in the wall of the esophagus. Feed material impacted in the esophagus is one cause of esophageal dilation (ectasia, megaesophagus). In NTP studies esophageal dilation has occurred primarily in female F344 rats administered a powdered diet. This lesion may result in mortality, suppurative foreign-body pneumonia, or rhinitis.
Recommendation:
Esophageal dilation should be diagnosed and graded based on the overall size of the dilated esophagus.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/esophagus/Dilation
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Dilation (esophagus). LabSmart 中文版:
https://www.labsmart.cn/ntp/esophagus-dilation.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#esophagus-dilation