上皮增生Epithelium Hyperplasia · 胆囊 · 肝胆系统 · NTP ntp-0425
诊断要点:胆囊黏膜或上皮增生在 NTP 研究中不常见,只要存在就应记录并给出严重程度分级。
病变描述
Figure 1、Figure 2 来自一个部分塌陷的正常胆囊。注意肌壁的厚度。胆囊增生从乳头状皱襞上的少数细胞到累及大部分黏膜的弥漫性乳头状突起不等(Figure 3、Figure 4,箭头)。衬覆上皮中可能存在玻璃样液滴(hyaline droplets)。
诊断与分级建议(NTP 共识)
胆囊黏膜或上皮增生在 NTP 研究中不常见,只要存在就应记录并给出严重程度分级。相关的严重病变,如炎症或玻璃样液滴蓄积,应单独诊断。病理学描述应明确所诊断病例的任何异常特征。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Figure 1 and Figure 2 are from a partially collapsed normal gallbladder. Note the thickness of the muscular wall. Gallbladder hyperplasia varies from a few cells on papillary folds to generalized papillary projections involving most of the mucosa ( Figure 3 and Figure 4 , arrows). Hyaline droplets may be present in the lining epithelium.
Recommendation:
Mucosal or epithelial hyperplasia of the gallbladder is uncommon in NTP studies and should be recorded whenever present and given a severity grade. Severe associated lesions such as inflammation or hyaline droplet accumulation should be diagnosed separately. The pathology narrative should define any unusual features of the case(s) being diagnosed.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/hepatobiliary-system/gallbladder/Epithelium-Hyperplasia
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Epithelium Hyperplasia (gallbladder). LabSmart 中文版:
https://www.labsmart.cn/ntp/gallbladder-epithelium-hyperplasia.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#gallbladder-epithelium-hyperplasia