张力性脂质沉积症Tension Lipidosis · 肝 · 肝胆系统 · NTP ntp-0402
诊断要点：对该病变的观察取决于组织采样和切片平面，并非必然见于所有动物。鼓励将其记录为张力性脂质沉积，以避免与肝实质的其他局灶性（focal）改变相混淆。
病变描述
张力性脂质沉积（tension lipidosis，Figure 1，箭头）是发生于小鼠胆囊附近及镰状韧带附着处的局灶性（focal）胞质空泡化。此病变不被视为一种病理实体，但应与其他形式的胞质空泡化相鉴别。理论上，该病变可见于任何年龄。镰状韧带是胎儿腹侧系膜的残余，从肝门附近的膈区延伸至腹侧腹壁。张力性脂质沉积通常见于中叶脏膜面正下方。
诊断与分级建议（NTP 共识）
对该病变的观察取决于组织采样和切片平面，并非必然见于所有动物。鼓励将其记录为张力性脂质沉积，以避免与肝实质的其他局灶性（focal）改变相混淆。病理学描述应提及这是一种无病理学意义的改变。相关链接：肝脏 - 脂肪变（Liver - Fatty Change）
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Tension lipidosis ( Figure 1 , arrows) is a focal cytoplasmic vacuolization that occurs near the gallbladder and the attachment of the falciform ligament in mice. This is not considered a pathologic entity but should be distinguished from other forms of cytoplasmic vacuolation. Theoretically, it could be seen at any age. The falciform ligament is a remnant of the ventral mesentery of the fetus that extends from the diaphragmatic area near the liver hilus to the ventral abdominal wall. Tension lipidosis is typically seen just below the parietal surface of the median lobe.
Recommendation：
Observation of this lesion is dependent on tissue sampling and plane of section and will not necessarily be seen in all animals. Documentation as tension lipidosis is encouraged to avoid confusion with other focal changes in hepatic parenchyma. The pathology narrative should mention that it is a change without pathologic significance. Related Links: Liver - Fatty Change
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/hepatobiliary-system/liver/TensionLipidosis
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Tension Lipidosis (liver). LabSmart 中文版：
https://www.labsmart.cn/ntp/liver-tension-lipidosis.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#liver-tension-lipidosis