萎缩Atrophy · 泪腺 · 特殊感觉系统 · NTP ntp-0325
诊断要点:泪腺萎缩应当作出诊断并赋予严重程度分级。任何相关的反应性纤维化不应单独诊断,除非其严重程度足以支持单独诊断,但可在叙述中描述。
病变描述
泪腺萎缩(Figure 1、Figure 2)在大鼠和小鼠中常见,为自发性衰老性改变,也可作为创伤、炎症或其他原发性泪腺疾病的后遗症。其特征为局灶性(focal)至融合性分布的腺泡皱缩区,衬覆小而低至扁平的立方细胞,并由不同程度增多的纤维性间质支撑。
诊断与分级建议(NTP 共识)
泪腺萎缩应当作出诊断并赋予严重程度分级。任何相关的反应性纤维化不应单独诊断,除非其严重程度足以支持单独诊断,但可在叙述中描述。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Lacrimal gland atrophy ( Figure 1 and Figure 2 ) occurs commonly in rats and mice as a spontaneous aging change and can also be a sequela of trauma, inflammation, or other primary lacrimal gland disease. It is characterized by focal to confluent areas of shrunken acini lined by small, low to flattened cuboidal cells and supported by variably increased fibrous stroma.
Recommendation:
Lacrimal gland atrophy should be diagnosed and assigned a severity grade. Any associated reactive fibrosis should not be diagnosed separately, unless warranted by severity, but can be described in the narrative.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/lacrimal-gland/Atrophy
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Atrophy (lacrimal-gland). LabSmart 中文版:
https://www.labsmart.cn/ntp/lacrimal-gland-atrophy.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#lacrimal-gland-atrophy