滑囊囊肿Bursa Cyst · 卵巢 · 雌性生殖系统 · NTP ntp-0515
诊断要点:卵巢腔上囊囊肿应予以诊断,但作为背景性病变发生的囊肿无需分级。对于腔上囊囊肿,诊断应包括囊肿类型/部位作为修饰词(即 Ovary, Bursa - Cyst)。
病变描述
腔上囊囊肿(Bursal cyst)(Figure 1、Figure 2)的特征是卵巢囊或腔上囊扩张。腔上囊囊肿在老龄小鼠和大鼠尸检时常见。这些囊肿由单层扁平上皮衬覆(Figure 3)。腔上囊囊肿应与真性卵巢囊肿或卵巢旁囊肿相鉴别。腔上囊囊肿包裹卵巢,可能造成压迫,但不存在于卵巢内。通常,膨胀的腔上囊在剖检时塌陷,显露其中完整的卵巢,而真性卵巢囊肿位于卵巢实质内,尸检时通常可完整剥离。卵巢旁囊肿存在于卵巢内和/或邻近卵巢,由扁平、立方或柱状上皮衬覆;上皮可具纤毛,并可见与卵巢系膜内卵巢旁结构的连接。腔上囊囊肿的发病机制尚未阐明。
诊断与分级建议(NTP 共识)
卵巢腔上囊囊肿应予以诊断,但作为背景性病变发生的囊肿无需分级。对于腔上囊囊肿,诊断应包括囊肿类型/部位作为修饰词(即 Ovary, Bursa - Cyst)。如果认为囊肿与受试物相关,可对其进行分级以充分表征受试物效应。如适用,诊断中可包括“双侧(bilateral)”和“multiple”这两个术语。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Bursal cysts ( Figure 1 and Figure 2 ) are characterized by dilation of the ovarian capsule, or bursa. Bursal cysts are frequently found in aged mice and rats at necropsy. These cysts are lined by a simple squamous epithelium ( Figure 3 ). Bursal cysts should be distinguished from true ovarian or paraovarian cysts. Bursal cysts envelop the ovary and may cause compression but are not present within the ovary. Typically, a distended bursa collapses at dissection, disclosing an intact ovary within it, whereas a true ovarian cyst is found within the ovarian parenchyma and may generally be dissected intact at necropsy. Paraovarian cysts are present within and/or adjacent to the ovary and are lined by flattened, cuboidal or columnar epithelium; the epithelium may be ciliated, and a connection to paraovarian structures in the mesovarium may be seen. The pathogenesis of bursal cysts has not been elucidated.
Recommendation:
Ovarian bursal cysts should be diagnosed, but cysts occurring as background lesions need not be graded. In the case of a bursal cyst, the diagnosis should include the type of cyst/location as a modifier (i.e., Ovary, Bursa - Cyst). If the cysts are thought to be treatment related, they may be graded to fully characterize the treatment effect. If applicable, the terms "bilateral" and "multiple" may be included in the diagnosis.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/Bursa-Cyst
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Bursa Cyst (ovary). LabSmart 中文版:
https://www.labsmart.cn/ntp/ovary-bursa-cyst.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#ovary-bursa-cyst