骨性化生Metaplasia Osseous · 卵巢 · 雌性生殖系统 · NTP ntp-0525
诊断要点：卵巢——化生，骨性（Metaplasia, Osseous）只要存在即应诊断并分级。
病变描述
卵巢骨性化生（osseous metaplasia）（Figure 1、Figure 2）的特征为边界清楚、无包膜的病灶，由骨小梁构成，骨小梁表面衬覆成骨细胞和破骨细胞；还可见无定形无细胞性嗜碱性物质团块，最可能是钙盐的矿化沉积物，并可见邻近卵巢实质轻度受压。卵巢化生是一种与衰老和卵巢萎缩相关的改变。骨性化生偶有报道，但其机制尚未阐明。
诊断与分级建议（NTP 共识）
卵巢——化生，骨性（Metaplasia, Osseous）只要存在即应诊断并分级。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Ovarian osseous metaplasia ( Figure 1 and Figure 2 ) is characterized by a well-circumscribed, unencapsulated focus composed of bony trabeculae lined by osteoblasts and osteoclasts; there may also be clumps of amorphous acellular basophilic material, which are most likely mineralized deposits of calcium salts, and mild compression of adjacent ovarian parenchyma. Ovarian metaplasia is a change associated with aging and ovarian atrophy. Osseous metaplasia has been occasionally reported, but the mechanism has not been elucidated.
Recommendation：
Ovary - Metaplasia, Osseous should be diagnosed and graded whenever present.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/MetaplasiaOsseous
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Metaplasia Osseous (ovary). LabSmart 中文版：
https://www.labsmart.cn/ntp/ovary-metaplasia-osseous.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#ovary-metaplasia-osseous