矿化Mineralization · 前列腺 · 雄性生殖系统 · NTP ntp-0446
诊断要点:在前列腺的组织病理学评价中,应诊断矿化并给出严重程度分级。如有可能,应确定受累的叶,并在组织标识中注明。
病变描述
矿化(mineralization)的特征是局灶性(focal)至弥漫性(diffuse)的嗜碱性、各向异性、不规则颗粒状物质蓄积,可累及腺泡(Figure 1、Figure 2)或血管壁。此种程度的矿化不常见。可能发生两种类型的矿化:转移性(metastatic,与血钙水平升高相关的正常组织钙化)或营养不良性(dystrophic,与血钙水平升高无关的异常或退化组织中的矿物质沉积)。
诊断与分级建议(NTP 共识)
在前列腺的组织病理学评价中,应诊断矿化并给出严重程度分级。如有可能,应确定受累的叶,并在组织标识中注明。如果成对的叶均受累,诊断应注明为双侧性,严重程度以受累较重的叶为准。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Mineralization is characterized by focal to diffuse accumulation of basophilic, anisotropic, irregular granular material that may involve the glandular acini ( Figure 1 and Figure 2 ) or vessel wall. This degree of mineralization is unusual. Two types of mineralization may occur: metastatic (calcification of normal tissue associated with high blood levels of calcium) or dystrophic (mineral deposits in abnormal or degenerating tissue not associated with increased blood levels of calcium).
Recommendation:
Mineralization should be diagnosed during histopathologic evaluation of prostate and given a severity grade. The affected lobe(s) should be identified if possible and indicated in the tissue identification. If paired lobes are affected, the diagnosis should be indicated as bilateral and the degree of severity based on more severely affected lobe.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/prostate/Mineralization
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Mineralization (prostate). LabSmart 中文版:
https://www.labsmart.cn/ntp/prostate-mineralization.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#prostate-mineralization