血管扩张Angiectasis · 骨骼肌 · 骨骼肌肉系统 · NTP ntp-0595
诊断要点:血管扩张出现时,应当作出诊断并赋予严重程度分级。
病变描述
血管扩张(angiectasis)是一种非增殖性病变,其中原有的血管腔扩张并变得显著(Figure 1、Figure 2)。血管由单层扁平内皮细胞衬覆,内皮细胞在外观、数量和大小上均正常。血管扩张通常是一种偶然性病变,其病因学和发病机制往往不清楚。将血管扩张与血管瘤(hemangioma)区分开来很重要。这可能有难度,因为这种区分并不总是显而易见,而且血管扩张性病变可出现在血管瘤的区域。血管瘤往往是边界清楚、无包膜的肿块,由紧密排列的扩张血管腔组成,压迫周围组织。虽然血管腔由单层分化良好的内皮细胞衬覆,但内皮细胞核通常数量增多并轻度增大。一般来说,缺乏内皮细胞增殖和/或核异型性可将血管扩张与肿瘤性血管病变区分开来。此外,血管扩张通常不表现为边界清楚的肿块;扩张的血管通道常不规则地穿行于组织中。
诊断与分级建议(NTP 共识)
血管扩张出现时,应当作出诊断并赋予严重程度分级。
图谱


英文原文
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Comment:
Angiectasis is a nonproliferative lesion in which preexisting vascular spaces are dilated and prominent ( Figure 1 and Figure 2 ). The vessels are lined by a single layer of flat endothelium in which the endothelial cells are normal in appearance, number, and size. Angiectasis is typically an incidental lesion, and its etiology and pathogenesis are often obscure. It is important to distinguish angiectasis from a hemangioma. This can be difficult because the distinction is not always obvious and angiectatic lesions can appear in regions of hemangiomas. Hemangiomas tend to be well-circumscribed, unencapsulated masses composed of tightly packed, dilated vascular spaces that compress surrounding tissues. While the vascular spaces are lined by a single layer of well-differentiated endothelium, endothelial nuclei are typically increased in number and slightly enlarged. In general, the absence of endothelial cell proliferation and/or nuclear atypia differentiates angiectasis from a neoplastic vascular lesion. In addition, angiectasis does not typically present as a well-circumscribed mass; the dilated vascular channels often course irregularly through the tissue.
Recommendation:
When present, angiectasis should be diagnosed and assigned a severity grade.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/skeletal-muscle/Angiectasis
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Angiectasis (skeletal-muscle). LabSmart 中文版:
https://www.labsmart.cn/ntp/skeletal-muscle-angiectasis.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#skeletal-muscle-angiectasis