囊肿Cyst · 骨骼肌 · 骨骼肌肉系统 · NTP ntp-0587
诊断要点:虽然骨骼肌囊肿常为偶然性病变,但其存在应当记录。不需要赋予严重程度分级。伴随的肌病性改变不需要单独诊断,除非严重程度确有必要。
病变描述
骨骼肌内可发生上皮衬覆的囊肿(Figure 1、Figure 2、Figure 3、Figure 4)。根据其大小,可发生相邻肌纤维的压迫。囊性结构可为空虚,或含有数量不等的角蛋白、毛发碎片和/或细胞碎片。关节是囊性病变发生的常见部位;然而,滑膜囊肿在这些区域更为常见。滑膜囊肿由滑膜细胞衬覆,含液体,并可能与相邻关节相通。寄生虫性囊肿有时存在于骨骼肌内。虽然鼠肉孢子虫(Sarcocystis muris)确实感染大鼠和小鼠的骨骼肌,但在管理良好的啮齿动物种群中并不常见,且通常不伴有炎症。若存在伴随病变,其性质主要为退行性。
诊断与分级建议(NTP 共识)
虽然骨骼肌囊肿常为偶然性病变,但其存在应当记录。不需要赋予严重程度分级。伴随的肌病性改变不需要单独诊断,除非严重程度确有必要。应在描述中说明衬覆细胞的性质、腔内容物的存在及性质,以及对相邻骨骼肌纤维的局部影响。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Epithelium-lined cysts can develop in skeletal muscle ( Figure 1 , Figure 2 , Figure 3 , and Figure 4 ). Depending upon their size, compression of adjacent myofibers can occur. The cystic structures can be empty or contain variable amounts of keratin, hair fragments, and/or cellular debris. Joints are a common place for cystic lesions to occur; however, synovial cysts are more common in these regions. Synovial cysts are lined with synovial cells, contain fluid, and may communicate with the adjacent joint. Parasitic cysts are sometimes present within skeletal muscle. While Sarcocystis muris does infect skeletal muscle in rats and mice, it is not common in well-managed rodent colonies and is generally not associated with accompanying inflammation. If accompanying lesions are present, they are primarily degenerative in nature.
Recommendation:
While skeletal muscle cysts are often incidental lesions, their presence should be recorded. A severity grade does not need to be assigned. Accompanying myopathic changes do not need to be diagnosed separately unless warranted by severity. The nature of the lining cells, presence and nature of luminal contents, and regional effects on adjacent skeletal muscle fibers should be addressed in the narrative.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/skeletal-muscle/Cyst
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Cyst (skeletal-muscle). LabSmart 中文版:
https://www.labsmart.cn/ntp/skeletal-muscle-cyst.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#skeletal-muscle-cyst