精子肉芽肿Sperm Granuloma · 睾丸 · 雄性生殖系统 · NTP ntp-0472

依据美国国家毒理学计划(NTP)Nonneoplastic Lesion Atlas 整理 · 中文译文与诊断建议 · 仅供科研使用,不用于临床诊断

一句话结论:精子肉芽肿(sperm granuloma)在睾丸中不常见;在附睾中则常见得多。
诊断要点:精子肉芽肿只要存在就应诊断。不必对精子肉芽肿进行分级,除非病理学家认为分级有助于将该病变识别为与处理相关。

病变描述

精子肉芽肿(sperm granuloma)在睾丸中不常见;在附睾中则常见得多。它们最常作为曲细精管或睾丸网内精子淤滞的继发结果出现。精子肉芽肿可进展为血-睾屏障的破坏,并使受累的生精小管被肉芽肿性炎症所取代。这最常见表现为偶然发现的背景性病变。

诊断与分级建议(NTP 共识)

精子肉芽肿只要存在就应诊断。不必对精子肉芽肿进行分级,除非病理学家认为分级有助于将该病变识别为与处理相关。相关病变,如变性,应单独诊断。分页 图1,共1张 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠,但其在小鼠或大鼠中的表现相同。放大图像 所有图像 放大所有图像 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠,但其在小鼠或大鼠中的表现相同。"> 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠,但其在小鼠或大鼠中的表现相同。" /> 睾丸——雄性仓鼠的精子肉芽肿。尽管该精子肉芽肿示例来自仓鼠,但其在小鼠或大鼠中的表现相同。

图谱

精子肉芽肿(睾丸)组织学图谱 1
图 1 · 精子肉芽肿 · 来源:NTP NNL Atlas

英文原文

展开 NTP 官方英文描述与建议

Comment:
Sperm granulomas are uncommon findings in the testis; they are much more common in the epididymis. They most often occur as a sequel to sperm stasis within a tubule or within the rete testis. Sperm granulomas may progress to disruption of the blood-testis barrier and replacement of the affected seminiferous tubule with granulomatous inflammation. This is most commonly seen as an incidental background lesion.

Recommendation:
Sperm granulomas should be diagnosed whenever present. It is not necessary to grade sperm granulomas, unless the pathologist feels that grading would help identify the lesion as being treatment-related. Associated lesions, such as degeneration, should be diagnosed separately. Pagination Figure 1 of 1 Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same. Enlarge Image All Images Enlarge All Images Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same. "> Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same. " /> Testis - Sperm granuloma in a male hamster. Though this example of a sperm granuloma is from a hamster, its appearance in a mouse or rat would be the same.

来源与引用

原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/SpermGranuloma

图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。

建议引用格式:NTP Nonneoplastic Lesion Atlas. Sperm Granuloma (testis). LabSmart 中文版: https://www.labsmart.cn/ntp/testis-sperm-granuloma.html

中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#testis-sperm-granuloma

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