精液囊肿Spermatocele · 睾丸 · 雄性生殖系统 · NTP ntp-0473

依据美国国家毒理学计划(NTP)Nonneoplastic Lesion Atlas 整理 · 中文译文与诊断建议 · 仅供科研使用,不用于临床诊断

一句话结论:精液囊肿(spermatocele)是指精子在生精小管或管道内囊性积聚或阻塞,导致其直径增大至正常直径的两倍以上。
诊断要点:精液囊肿存在时应予以诊断,但无需分级。仅在认为与处理相关时,才应在病理学叙述中讨论。

病变描述

精液囊肿(spermatocele)是指精子在生精小管或管道内囊性积聚或阻塞,导致其直径增大至正常直径的两倍以上。若直径小于此值,则应使用“精子停滞(sperm stasis)”一词(见睾丸-精子停滞)。若积聚伴有炎症反应,则应使用“精子肉芽肿(sperm granuloma)”一词(见睾丸-精子肉芽肿)。精液囊肿更常见于附睾,但有时也见于睾丸内,尤其是小鼠的包膜下睾丸网内(Figure 1,星号及Figure 2)。精液囊肿可与输出小管液体吸收减少相关,导致精子在睾丸网及邻近生精小管内阻塞和梗阻。这可能是化学物诱导的所见,但一般而言,精液囊肿是偶发性的、与年龄相关的所见。已有描述年龄相关的生殖细胞变性(germ cell degeneration)与精液囊肿形成之间的关联。

诊断与分级建议(NTP 共识)

精液囊肿存在时应予以诊断,但无需分级。仅在认为与处理相关时,才应在病理学叙述中讨论。存在双侧受累时应予以记录。相关链接:睾丸-精子停滞 睾丸-精子肉芽肿

图谱

精液囊肿(睾丸)组织学图谱 1
图 1 · 精液囊肿 · 来源:NTP NNL Atlas
精液囊肿(睾丸)组织学图谱 2
图 2 · 精液囊肿 · 来源:NTP NNL Atlas

英文原文

展开 NTP 官方英文描述与建议

Comment:
A spermatocele refers to the cystic accumulation or impaction of spermatozoa in a seminiferous tubule or duct causing it to increase to more than twice its normal diameter. If the diameter is less than this, the term “sperm stasis” should be used (see Testis - Sperm Stasis ). If the accumulation is accompanied by an inflammatory reaction, the term “sperm granuloma” should be used (see Testis - Sperm Granuloma ). Spermatoceles occur more commonly in the epididymis, but they are also sometimes seen within the testis, and particularly within the subcapsular rete testis of the mouse ( Figure 1 , asterisk and Figure 2 ). Spermatoceles can occur in association with reduced fluid absorption in the efferent ducts leading to sperm impaction and obstruction within the rete testis and adjacent seminiferous tubules. This can be a chemically induced finding, but in general spermatoceles are incidental, age-related findings. An association between age-related germ cell degeneration and spermatocele formation has been described.

Recommendation:
Spermatocele should be diagnosed when present, but need not be graded. They should be discussed in the pathology narrative only if they are considered treatment related. Bilateral involvement should be recorded when present. Related Links: Testis - Sperm Stasis Testis - Sperm Granuloma

来源与引用

原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/Spermatocele

图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。

建议引用格式:NTP Nonneoplastic Lesion Atlas. Spermatocele (testis). LabSmart 中文版: https://www.labsmart.cn/ntp/testis-spermatocele.html

中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#testis-spermatocele

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