出血Hemorrhage · 子宫 · 雌性生殖系统 · NTP ntp-0528
诊断要点:子宫-出血(Uterus - Hemorrhage)应诊断并分级。如果它是继发于其他过程(例如炎症、肿瘤),除非严重程度 warrant,否则不应诊断,但应在病理学叙述中描述。
病变描述
子宫出血(Uterine hemorrhage)(Figure 1、Figure 2)偶见于大鼠和小鼠。它常与F344大鼠的单核细胞白血病(mononuclear cell leukemia)相关。当发生慢性出血时,可见含铁血黄素负载的巨噬细胞(hemosiderin-laden macrophages)、胆固醇裂隙(cholesterol clefts)、营养不良性钙化或矿化(dystrophic calcification or mineralization)以及纤维化(fibrosis)。这些变化可发生于子宫腔、子宫内膜和/或子宫肌层。必须仔细检查子宫出血,以寻找内皮增生的证据,提示存在 underlying process,如内皮增生(endothelial hyperplasia)、血管瘤(hemangioma)或血管肉瘤(hemangiosarcoma)。
诊断与分级建议(NTP 共识)
子宫-出血(Uterus - Hemorrhage)应诊断并分级。如果它是继发于其他过程(例如炎症、肿瘤),除非严重程度 warrant,否则不应诊断,但应在病理学叙述中描述。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Uterine hemorrhage ( Figure 1 and Figure 2 ) is seen occasionally in rats and mice. It is often associated with mononuclear cell leukemia in F344 rats. When chronic hemorrhage occurs, hemosiderin-laden macrophages, cholesterol clefts, dystrophic calcification or mineralization, and fibrosis may be evident. This may occur in the lumen, endometrium, and/or myometrium. Uterine hemorrhage must be carefully examined for evidence of endothelial proliferation that would indicate the presence of an underlying process, such as endothelial hyperplasia, hemangioma, or hemangiosarcoma.
Recommendation:
Uterus - Hemorrhage should be diagnosed and graded. If it is secondary to another process (e.g., inflammation, neoplasia), it should not be diagnosed unless warranted by severity but should be described in the pathology narrative.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/Hemorrhage
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Hemorrhage (uterus). LabSmart 中文版:
https://www.labsmart.cn/ntp/uterus-hemorrhage.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#uterus-hemorrhage