坏死Necrosis · 子宫 · 雌性生殖系统 · NTP ntp-0529
诊断要点:子宫-坏死(Uterus - Necrosis)应予以诊断并分级。如果坏死继发于其他病变,如炎症(inflammation),则不应单独诊断,除非其严重程度足以支持单独诊断。
病变描述
子宫坏死(uterine necrosis)较为罕见,但其组织学表现与其他部位的坏死相似,初期表现为组织中的细胞死亡,特征为核固缩(nuclear pyknosis)和/或核碎裂(karyorrhexis)、胞质嗜酸性(cytoplasmic eosinophilia)以及细胞肿胀或皱缩。坏死的后果是肉芽组织(granulation tissue)和矿化(mineralization)(Figure 1、Figure 2)。子宫坏死可能由相关的动脉炎(arteritis)或血栓形成(thrombosis)及随后的组织梗死(infarction)引起(Figure 1、Figure 2)。
诊断与分级建议(NTP 共识)
子宫-坏死(Uterus - Necrosis)应予以诊断并分级。如果坏死继发于其他病变,如炎症(inflammation),则不应单独诊断,除非其严重程度足以支持单独诊断。继发于坏死的病变,如炎症或出血(hemorrhage),不应单独诊断,除非其严重程度足以支持单独诊断。如果病理学家认为该坏死代表梗死(infarct),应在病理学描述(pathology narrative)中注明。
图谱


英文原文
展开 NTP 官方英文描述与建议
Comment:
Uterine necrosis is rarely encountered, but the histology of the lesion is like necrosis elsewhere, with cell death in the tissue characterized by nuclear pyknosis and/or karyorrhexis, cytoplasmic eosinophilia, and cellular swelling or shrinkage initially. The consequence of necrosis is granulation tissue and mineralization ( Figure 1 and Figure 2 ). Uterine necrosis may occur due to associated arteritis or thrombosis and subsequent infarction of the tissue ( Figure 1 and Figure 2 ).
Recommendation:
Uterus - Necrosis should be diagnosed and graded. If the necrosis is secondary to another lesion, such as inflammation, it should not be diagnosed separately unless warranted by severity. Lesions secondary to necrosis, such as inflammation or hemorrhage, should not be diagnosed separately unless warranted by severity. The pathologist should note in the pathology narrative if the necrosis is thought to represent an infarct.
来源与引用
原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/Necrosis
图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。
建议引用格式:NTP Nonneoplastic Lesion Atlas. Necrosis (uterus). LabSmart 中文版:
https://www.labsmart.cn/ntp/uterus-necrosis.html
中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#uterus-necrosis