扩张Dilation · 阴道 · 雌性生殖系统 · NTP ntp-0562

依据美国国家毒理学计划(NTP)Nonneoplastic Lesion Atlas 整理 · 中文译文与诊断建议 · 仅供科研使用,不用于临床诊断

一句话结论:阴道扩张(Figure 1、Figure 2)通常继发于阴道闭锁。在幼犬中,内胚层膜正常情况下封闭阴道,该膜通常在青春期消失,阴道随之通畅。
诊断要点:阴道——当切片上扩张原因不明显时,应诊断并分级为扩张。然而,若阴道闭锁且在切片上明显可见,则应作出阴道闭锁的诊断。

病变描述

阴道扩张(Figure 1、Figure 2)通常继发于阴道闭锁。在幼犬中,内胚层膜正常情况下封闭阴道,该膜通常在青春期消失,阴道随之通畅。若此过程未发生,其后果即为阴道囊性扩张。这种扩张也可能与子宫积黏液、炎症及上皮增生相关。

诊断与分级建议(NTP 共识)

阴道——当切片上扩张原因不明显时,应诊断并分级为扩张。然而,若阴道闭锁且在切片上明显可见,则应作出阴道闭锁的诊断。继发性病变,如炎症,除非严重程度足以支持,否则不应单独诊断。

图谱

扩张(阴道)组织学图谱 1
图 1 · 扩张 · 来源:NTP NNL Atlas
扩张(阴道)组织学图谱 2
图 2 · 扩张 · 来源:NTP NNL Atlas

英文原文

展开 NTP 官方英文描述与建议

Comment:
Dilation of the vagina ( Figure 1 and Figure 2 ) usually occurs secondary to an imperforate vagina. An endodermal membrane normally occludes the vagina in the pup, and this typically disappears at puberty and the vagina becomes patent. When this does not happen, the consequence is cystic dilation of the vagina. This dilation may also be associated with mucometra, inflammation, and hyperplasia of the epithelium.

Recommendation:
Vagina - Dilatation should be diagnosed and graded when the cause of the dilation is not apparent on the slide. However, if the vagina is imperforate, and this is apparent on the slide, then the diagnosis of imperforate vagina should be made. Secondary lesions, such as inflammation, should not be diagnosed separately unless warranted by severity.

来源与引用

原始条目:https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/vagina/Dilation

图谱总目录:NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品(公有领域),可引用;引用时请标注来源。

建议引用格式:NTP Nonneoplastic Lesion Atlas. Dilation (vagina). LabSmart 中文版: https://www.labsmart.cn/ntp/vagina-dilation.html

中文图谱总页(可展开对照全部 595 条):https://www.labsmart.cn/ntp-atlas.html#vagina-dilation

上皮增生囊肿坏死基质肥大溃疡炎症