矿化Mineralization · 输精管 · 雄性生殖系统 · NTP ntp-0487
诊断要点：矿化应当被诊断并分级。如果其作为全身性反应发生于多个组织，则不必单独诊断输精管内的矿化。
病变描述
矿化（mineralization）的特征是嗜碱性、细至粗颗粒状至无定形物质的蓄积（箭头），通常不伴有组织结构的变形（Figure 1、Figure 2）。输精管（ductus deferens）内的矿化不常见，很可能是与化学处理无直接关联的偶然发现。矿化可有两种类型：转移性（metastatic，与血钙水平升高相关的正常组织钙化）或营养不良性（dystrophic，与血钙水平升高无关的异常或退化组织中的矿物质沉积）。当呈全身性时，转移性矿化可存在于多个器官。
诊断与分级建议（NTP 共识）
矿化应当被诊断并分级。如果其作为全身性反应发生于多个组织，则不必单独诊断输精管内的矿化。然而，其在输精管内的存在可在病理学叙述中提及。
图谱
英文原文
展开 NTP 官方英文描述与建议
Comment：
Mineralization is characterized by accumulation of basophilic, fine to coarsely granular to amorphous material (arrows), often without distortion of the histoarchitecture ( Figure 1 and Figure 2 ). Mineralization in the ductus deferens is unusual and is likely an incidental finding not directly associated with chemical treatment. Two types of mineralization may occur: metastatic (calcification of normal tissue associated with high blood levels of calcium) or dystrophic (mineral deposits in abnormal or degenerating tissue not associated with increased blood levels of calcium). When systemic, metastatic mineralization can be present in multiple organs.
Recommendation：
Mineralization should be diagnosed and graded. If it occurs in multiple tissues as a systemic response, it is not necessary to separately diagnose mineralization in the ductus deferens. However, its presence in the ductus deferens may be mentioned in the pathology narrative.
来源与引用
原始条目：https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/ductus-deferens/Mineralization
图谱总目录：NTP Nonneoplastic Lesion Atlas。 内容属美国联邦政府作品（公有领域），可引用；引用时请标注来源。
建议引用格式：NTP Nonneoplastic Lesion Atlas. Mineralization (ductus-deferens). LabSmart 中文版：
https://www.labsmart.cn/ntp/ductus-deferens-mineralization.html
中文图谱总页（可展开对照全部 595 条）：https://www.labsmart.cn/ntp-atlas.html#ductus-deferens-mineralization